지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 96 - 100 (5page)
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초록· 키워드
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Ectopic adrenocorticotropic hormone (ACTH) syndrome is caused most frequently by a bronchial carcinoid tumor or by small cell lung cancer. Medullary thyroid carcinoma (MTC) is a rare etiology of ectopic ACTH syndrome. We describe a case of Cushing syndrome due to ectopic ACTH production from MTC in a 48-year-old male. He was diagnosed with MTC 14 years ago and underwent total thyroidectomy, cervical lymph node dissection and a series of metastasectomies. MTC was confirmed by the pathological examination of the thyroid and metastatic mediastinal lymph node tissues. Two years after his last surgery, he developed Cushingoid features, such as moon face and central obesity, accompanied by uncontrolled hypertension and new-onset diabetes. The laboratory results were compatible with ectopic ACTH syndrome. A bilateral adrenalectomy improved the clinical and laboratory findings that were associated with Cushing syndrome. This is the first confirmed case of ectopic ACTH syndrome caused by MTC in Korea.
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등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
Kebebew E / 2000 / Medullary thyroid carcinoma: clinical characteristics, treatment, prognostic factors, and a comparison of staging systems / Cancer 88:1139~1148
Barbosa SL / 2005 / Ectopic adrenocorticotropic hormone-syndrome in medullary carcinoma of the thyroid: a retrospective analysis and review of the literature / Thyroid 15:618~623
Isidori AM / 2006 / The ectopic adrenocorticotropin syndrome: clinical features, diagnosis, management, and long-term follow-up / J Clin Endocrinol Metab 91:371~377
Ilias I / 2005 / Cushing’s syndrome due to ectopic corticotropin secretion: twenty years’ experience at the National Institutes of Health / J Clin Endocrinol Metab 90:4955~4962
Sand M / 2007 / Simultaneous ectopic adrenocorticotropic hormone syndrome and adrenal metastasis of a medullary thyroid carcinoma causing paraneoplastic Cushing’s syndrome / Int Semin Surg Oncol 4:15
Barbosa SL / 2005 / Ectopic adrenocorticotropic hormone-syndrome in medullary carcinoma of the thyroid: a retrospective analysis and review of the literature / Thyroid 15:618~623
Isidori AM / 2006 / The ectopic adrenocorticotropin syndrome: clinical features, diagnosis, management, and long-term follow-up / J Clin Endocrinol Metab 91:371~377
Ilias I / 2005 / Cushing’s syndrome due to ectopic corticotropin secretion: twenty years’ experience at the National Institutes of Health / J Clin Endocrinol Metab 90:4955~4962
Sand M / 2007 / Simultaneous ectopic adrenocorticotropic hormone syndrome and adrenal metastasis of a medullary thyroid carcinoma causing paraneoplastic Cushing’s syndrome / Int Semin Surg Oncol 4:15
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