지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 710 - 715 (6page)
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초록· 키워드
오류제보하기
The aim of the present study was to evaluate the efficacy and toxicity of stereotactic body radiation therapy (SBRT) for low- to intermediate-risk prostate adenocarcinoma. Thirtynine patients were retrospectively reviewed. The SBRT was delivered using the CyberKnife with the fiducial tracking method combined with In-tempo imaging. The gross target volume, which included the prostate only, was delineated on the fused CT/MRI scans. The prescription dose was delivered every other day as 5 fractions of 7.5 Gy. Venous blood was obtained before and after SBRT to assess the prostate-specific antigen (PSA) level. Toxicity was evaluated using the CTCAE, v4.03. The median follow-up time was 30.0 months. The median initial PSA level was 7.7 ng/mL. PSA levels decreased in all patients treated with SBRT, and after 5 months, the median PSA was less than 2 ng/mL. The rate of overall 3-yr actuarial biochemical failure free survival was 93.9%. Acute side effects were generally comparable with those of previous studies. The PSA change and toxicity after SBRT for low- to intermediate-risk prostate adenocarcinoma indicates favorable biochemical responses and tolerable levels of toxicity. Additionally short course treatment may produce cost benefit and convenience to patients.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Jemal A / 2011 / Global cancer statistics / CA Cancer J Clin 61:69~90
Thompson I / 2007 / Guideline for the management of clinically localized prostate cancer: 2007 update / J Urol 177:2106~2131
Brenner DJ / 1999 / Fractionation and protraction for radiotherapy of prostate carcinoma / Int J Radiat Oncol Biol Phys 43:1095~1101
D’Souza WD / 2001 / Is the alpha/beta ratio for prostate cancer low? / Int J Radiat Oncol Biol Phys 51:1~3
King CR / 2001 / A simple analytic derivation suggests that prostate cancer alpha/beta ratio is low / Int J Radiat Oncol Biol Phys 51:213~214
Thompson I / 2007 / Guideline for the management of clinically localized prostate cancer: 2007 update / J Urol 177:2106~2131
Brenner DJ / 1999 / Fractionation and protraction for radiotherapy of prostate carcinoma / Int J Radiat Oncol Biol Phys 43:1095~1101
D’Souza WD / 2001 / Is the alpha/beta ratio for prostate cancer low? / Int J Radiat Oncol Biol Phys 51:1~3
King CR / 2001 / A simple analytic derivation suggests that prostate cancer alpha/beta ratio is low / Int J Radiat Oncol Biol Phys 51:213~214
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