지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 257 - 260 (4page)
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초록· 키워드
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Granulomatosis with polyangiitis (GPA) is a rare antineutrophil cytoplasmic antibody associated with systemic disease characterized by granulomas and vasculitis affecting small and medium vessels. Neurological manifestations in GPA are less frequent than classical manifestations, such as lung and kidney involvement, and cranial nerve palsies are much rarer. Cyclophosphamide and glucocorticoids have been conventionally administered as an initial induction immunosuppressive therapy for GPA. However, increasing evidence has demonstrated the efficacy and safety of rituximab, an anti-B cell monoclonal antibody, for the treatment of GPA. Herein, we describe a successful treatment of relapsing GPA with cranial nerve involvement using rituximab in a 56-year-old male patient who was previously treated with cyclophosphamide plus glucocorticoids.
목차
등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
Hoffman GS / 1992 / Travis WD, et al. Wegener granulomatosis:an analysis of 158 patients / Ann Intern Med 116:488~498
Seo P / 2004 / The antineutrophil cytoplasmic antibody-associated vasculitides / Am J Med 117:39~50
Stone JH / 2010 / Rituximab versus cyclophosphamide for ANCA-associated vasculitis / N Engl J Med 363:221~232
송은주 / 2010 / Rituximab과 cyclophosphamide 투여로 호전된 저항성 청피반성 혈관염 / 대한내과학회지 78(4):527~530
Nagashima T / 2000 / P-ANCA-positive Wegener's granulomatosis presenting with hypertrophic pachymeningitis and multiple cranial neuropathies: case report and review of literature / Neuropathology 20:23~30
Seo P / 2004 / The antineutrophil cytoplasmic antibody-associated vasculitides / Am J Med 117:39~50
Stone JH / 2010 / Rituximab versus cyclophosphamide for ANCA-associated vasculitis / N Engl J Med 363:221~232
송은주 / 2010 / Rituximab과 cyclophosphamide 투여로 호전된 저항성 청피반성 혈관염 / 대한내과학회지 78(4):527~530
Nagashima T / 2000 / P-ANCA-positive Wegener's granulomatosis presenting with hypertrophic pachymeningitis and multiple cranial neuropathies: case report and review of literature / Neuropathology 20:23~30
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