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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Objectives: The purpose of the present study was to analyze sociodemographic and clinical characteristics related to maintenance duration of naltrexone and acamprosate in patients with alcohol use disorder. Methods: The medical records including sociodemographic and clinical characteristics of 338 inpatients and outpatients with alcohol dependence and alcohol abuse were reviewed retrospectively. All patients were divided into < 30 days, 30 to 179 days, and ≧ 180 days naltrexone or acamprosate medication maintenance groups. Results: In contrast to the < 30 days maintenance group, naltrexone was used more commonly than acamprosate in the ≧ 180 days group (p = 0.017). This group had more psychiatric comorbidities (p = 0.011), less physical illness (p = 0.036), increases cases of admissions to psychiatric wards (p = 0.005), and additionally prescribed psychotropic medications (p <0.001) when compared with the < 30 days group. Conclusion: Although it is difficult to draw assertive conclusions solely based on the results from this study, it is apparent that extensive psychiatric comorbidities, history of psychiatric ward admissions, and fewer medical diseases characterized the long-term maintenance group in this study. In future, well-controlled, and more extended prospective research is needed to identify factors related to medical treatment and maintenance for alcohol use disorder.
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참고문헌 (26)
참고문헌 신청
The Survey of Mental Disorders in Korea 2016
Kishi T / 2013 / Antipsychotics for primary alcohol dependence: a systematic review and meta-analysis of placebo-controlled trials / J Clin Psychiatry 74:e642~e654
정우진 / 2006 / 음주의 사회경제적 비용 추계 / 예방의학회지 39(1):21~29
Mann K Hermann D / 2010 / Individualised treatment in alcohol-dependent patients / Eur Arch Psychiatry Clin Neurosci 260(Suppl 2):S116~S120
Jarosz J / 2013 / Naltrexone (50 mg) plus psychotherapy in alcohol-dependent patients: a metaanalysis of randomized controlled trials / Am J Drug Alcohol Abuse 39:144~160
Kishi T / 2013 / Antipsychotics for primary alcohol dependence: a systematic review and meta-analysis of placebo-controlled trials / J Clin Psychiatry 74:e642~e654
정우진 / 2006 / 음주의 사회경제적 비용 추계 / 예방의학회지 39(1):21~29
Mann K Hermann D / 2010 / Individualised treatment in alcohol-dependent patients / Eur Arch Psychiatry Clin Neurosci 260(Suppl 2):S116~S120
Jarosz J / 2013 / Naltrexone (50 mg) plus psychotherapy in alcohol-dependent patients: a metaanalysis of randomized controlled trials / Am J Drug Alcohol Abuse 39:144~160
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