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자료유형
학술저널
저자정보
André T.A. Gonçalves de Freitas (Bioscience Institute UNESP—São Paulo State University) Lino Lemonica (Universidade Estadual Paulista Júlio de Mesquita Filho) Julio De Faveri (Universidade Estadual Paulista Júlio de Mesquita Filho) Sergio Pereira (Universidade Estadual Paulista Júlio de Mesquita Filho) Maria D. Bedoya Henao (Universidade Estadual Paulista Júlio de Mesquita Filho)
저널정보
대한약침학회 Journal of Acupuncture & Meridian Studies Journal of Acupuncture & Meridian Studies Vol.9 No.1
발행연도
2016.1
수록면
16 - 21 (6page)

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Pain behavior and awareness are characterized by heightened alertness and anxiety, which begin to disappear as soon as the curative process starts. The present study aimed to quantify c-fos expression in rat spinal cords and brains after a surgical stimulus and with preoperative or postoperative acupuncture. Animals were randomly divided into preoperative and postoperative groups and were then further divided into control, manual acupuncture (MA), or electroacupuncture (EA) groups. Expression of c-fos was quantified using immunohistochemistry. The collected data were analyzed using the t test at a 5% probability level. Presurgery and postsurgery spinal cord c-fos expressions were similar in all of the treatment groups. In the control rats, c-fos expression was higher before surgery than after surgery, contradicting the expected outcome of acupuncture and preemptive analgesia. After treatment, the expression of c-fos in the brains of the rats in the MA and the EA groups was reduced compared with that of the rats in the control group. These findings suggest that acupuncture used as preemptive analgesia in rats is a useful model for studying its application in human treatment.

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