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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 513 - 520 (8page)
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BACKGROUND: Several injectable hydrogels have been developed extensively for a broad range of biomedical applications. Injectable hydrogels forming in situ through the change in external stimuli have the distinct properties of easy management and minimal invasiveness, and thus provide the advantage of bypassing surgical procedures for administration resulting in better patient compliance. METHODS: The injectable in situ-forming hydrogels can be formed irreversibly or reversibly under physiological stimuli. Among several external stimuli that induce formation of hydrogels in situ, in this review, we focused on the electrostatic interactions as the most simple and interesting stimulus. RESULTS: Currently, numerous polyelectrolytes have been reported as potential electrostatically interactive in situforming hydrogels. In this review, a comprehensive overview of the rapidly developing electrostatically interactive in situforming hydrogels, which are produced by various anionic and cationic polyelectrolytes such as chitosan, celluloses, and alginates, has been outlined and summarized. Further, their biomedical applications have also been discussed. CONCLUSION: The review concludes with perspectives on the future of electrostatically interactive in situ-forming hydrogels.
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참고문헌 (67)
참고문헌 신청
Zhang Z / 2016 / Injectable biomaterials for stem cell delivery and tissue regeneration / Expert Opin Biol Ther 17:49~62
Kim DY / 2015 / Stimuli-responsive injectable in situ-forming hydrogels for regenerative medicines / Polym Rev (Phila Pa) 55:407~452
Yang J / 2017 / Cell-laden hydrogels for osteochondral and cartilage tissue engineering / Acta Biomater 57:1~25
Andreea Luca / 2017 / Atelocollagen-based Hydrogels Crosslinked with Oxidised Polysaccharides as Cell Encapsulation Matrix for Engineered Bioactive Stromal Tissue / 조직공학과 재생의학 14(5):539~556
Xia T / 2017 / A review of gradient stiffness hydrogels used in tissue engineering and regenerative medicine / J Biomed Mater Res A 105:1799~1812
Kim DY / 2015 / Stimuli-responsive injectable in situ-forming hydrogels for regenerative medicines / Polym Rev (Phila Pa) 55:407~452
Yang J / 2017 / Cell-laden hydrogels for osteochondral and cartilage tissue engineering / Acta Biomater 57:1~25
Andreea Luca / 2017 / Atelocollagen-based Hydrogels Crosslinked with Oxidised Polysaccharides as Cell Encapsulation Matrix for Engineered Bioactive Stromal Tissue / 조직공학과 재생의학 14(5):539~556
Xia T / 2017 / A review of gradient stiffness hydrogels used in tissue engineering and regenerative medicine / J Biomed Mater Res A 105:1799~1812
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