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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 323 - 334 (12page)
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초록· 키워드
오류제보하기
Nonhuman primates (NHPs) have been widely used in reproductive biology, neuroscience, and drug development since a number of primate species are phylogenetically close to humans. In this review, we summarize the use of NHPs for nonclinical application in the reproductive system disorders including the loss or failure of an organ or tissue. Causes of infertility include congenital aplasia and acquired disorders of the reproductive organs. In addition, anti-cancer treatments can deplete ovarian follicles, leading to premature ovarian failure, infertility and long-term health risks. Along with a limited supply of human reproductive organs, anatomic/physiologic similarities to humans support the need for NHP models (New-World monkeys such as the common marmoset and Old-World monkeys such as cynomolgus and rhesus monkeys) to promote the advances in female infertility studies. For maintaining and executing animal studies using NHP, special protocols including animal care, anesthetic protocol, surgical technique, and immunosuppressive protocol are necessary. With a growing interest in the potential therapies such as endometrial tissue engineering, and ovary/follicle cryopreservation and grafting in Korea, this review can be useful in selecting appropriate animal models and can bridge between nonclinical studies and clinical applications by providing detailed information on the use of NHPs in the field of reproductive organ disorders.
목차
등록된 정보가 없습니다.
참고문헌 (111)
참고문헌 신청
Talmor A / 2015 / Female obesity and infertility / Best Pract Res Clin Obstet Gynaecol 29:498~506
Cates W / 1985 / Worldwide patterns of infertility: is Africa different? / Lancet 2:596~598
Practice Committee of the American Society for Reproductive Medicine / 2006 / Effectiveness and treatment for unexplained infertility / Fertil Steril 86:S111~S114
Griffin JE / 1976 / Congenital absence of the vagina. The Mayer-Rokitansky-Kuster-Hauser syndrome / Ann Intern Med 85:224~236
Nahum GG / 1998 / Uterine anomalies. How common are they, and what is their distribution among subtypes? / J Reprod Med 43:877~887
Cates W / 1985 / Worldwide patterns of infertility: is Africa different? / Lancet 2:596~598
Practice Committee of the American Society for Reproductive Medicine / 2006 / Effectiveness and treatment for unexplained infertility / Fertil Steril 86:S111~S114
Griffin JE / 1976 / Congenital absence of the vagina. The Mayer-Rokitansky-Kuster-Hauser syndrome / Ann Intern Med 85:224~236
Nahum GG / 1998 / Uterine anomalies. How common are they, and what is their distribution among subtypes? / J Reprod Med 43:877~887
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