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논문 기본 정보

자료유형
학술저널
저자정보
Ramish Riaz (Fatima Jinnah Women University Rawalpindi Pakistan) Nosheen Masood (Fatima Jinnah Women University Rawalpindi Pakistan) Arfa Benish (Fatima Jinnah Women University Rawalpindi Pakistan)
저널정보
대한장연구학회 Intestinal research Intestinal research Vol.15 No.2
발행연도
2017.1
수록면
203 - 207 (5page)

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Background/Aims: Colorectal cancer has long been considered disease of the West, typically occurring in old age; however,the incidence is rising in Asia. The pattern of disease is quite different in Asia, occurring at a younger age and at an advancedstage. Recognition of disease at an early stage is still a challenge for physicians. Few data are available regarding young-onsetcolorectal cancer in Pakistan. We conducted this study to fill this gap and provide deeper insight into clinical symptoms andhistopathological features of young-onset colorectal cancer. Methods: We collected data regarding clinical features by directlyinterviewing patients and obtaining histopathological data from hospital records. Patients aged less than 50 years were includedin the study. Statistical analysis was performed using IBM SPSS version 20.0. Results: Results in 105 patients showed meanage at diagnosis was 35.90±9.39, with male predominance; the majority of patients had no family history of colorectal cancer. Most patients had left-sided tumors with advance stage and intermediate grade (grade 2). Mucinous histology was common. Rectal bleeding was the first symptom for left-sided tumors, whereas most of the right-sided lesions presented with sudden obstruction. Conclusions: Painless rectal bleeding in the early thirties should alert physicians to advise appropriate investigation,as the majority of young-onset colorectal cancer patients develop painless bleeding 2 to 3 years before appearance of othersymptoms.

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