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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 116 - 120 (5page)
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Microalbuminuria is a key indicator for the treatment of cardiovascular or cerebrovascular diseases and death. Therefore, sensitive and specific detection methods of HSA in biological fluids especially in low concentration are necessary in diagnosis and preventive medicine. Here, nanostructured electrical immunosensor is demonstrated for the rapid, sensitive and selective detection of human serum albumin (HSA), using single-walled carbon nanotube (swCNT) field-effect transistor (FETs) functionalized with monoclonal anti-human serum albumin (mAHSA) via simple coating. The selective binding of HSA with mAHSA on the surface of swCNT induces the electrostatic gating effect to the swCNT-FET. The resulting sensor exhibited high sensitivity toward HSA in real time, with good selectivity. The proposed method provides a powerful platform for a real time, sensitive and selective monitoring of HSA in biological fluids.
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등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Moina, C. / 2012 / Fundamentals and Applications of Immunosensors, Advances in Immunoassay Technology / InTech
Ricci, F. / 2007 / A review on novel developments and applications of immunosensors in food analysis / Anal. Chim. Acta 605:111~129
Lim, S. A. / 2016 / Electrochemical immunosensors and their recent nanomaterial-based signal amplification strategies: a review / RSC Adv. 6:24995~25014
Li, M. / 2013 / Three-dimensional hierarchical plasmonic nano-architecture enhanced surface-enhanced Raman scattering immunosensor for cancer biomarker detection in blood plasma / Acs Nano 7:4967~4976
Pei, X. / 2013 / Sandwich-type immunosensors and immunoassays exploiting nanostructure labels: A review / Anal. Chim. Acta 758:1~18
Ricci, F. / 2007 / A review on novel developments and applications of immunosensors in food analysis / Anal. Chim. Acta 605:111~129
Lim, S. A. / 2016 / Electrochemical immunosensors and their recent nanomaterial-based signal amplification strategies: a review / RSC Adv. 6:24995~25014
Li, M. / 2013 / Three-dimensional hierarchical plasmonic nano-architecture enhanced surface-enhanced Raman scattering immunosensor for cancer biomarker detection in blood plasma / Acs Nano 7:4967~4976
Pei, X. / 2013 / Sandwich-type immunosensors and immunoassays exploiting nanostructure labels: A review / Anal. Chim. Acta 758:1~18
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