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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한예방치과학회 International Journal of Clinical Preventive Dentistry International Journal of Clinical Preventive Dentistry Vol.14 No.1
- 발행연도
- 2018.1
- 수록면
- 1 - 10 (10page)
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초록· 키워드
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The protective effects of milk and milk products against dental caries, due to micellar casein or caseinopeptide derivatives, have been demonstrated in various animal and human in situ studies. Among all the remineralising agents, casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) technology has shown the most promising scientific evidence to support its use in prevention and reversal of carious lesions. CPP-ACP complex acts as a calcium phosphate reservoir and buffer the activities of free calcium and phosphate ions in the plaque. Calcium phosphate stabilized by CPP produces a metastable solution supersaturated with respect to the amorphous and crystalline calcium phosphate phases, thereby depressing enamel demineralisation and enhancing mineralisation. CPP-ACP provides new avenue for the remineralisation of noncavitated caries lesions. The objective of this article was to review the clinical trials of CPP-ACP complex and highlight its evidence based applications in dentistry.
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참고문헌 (86)
참고문헌 신청
Featherstone JD / 2006 / Caries prevention and reversal based on the caries balance / Pediatr Dent 28:128~132
Featherstone JD / 1993 / Effect of whole saliva components on enamel demineralization in vitro / Crit Rev Oral Biol Med 4:357~362
Silverstone LM / 1983 / Remineralization and enamel caries: new concepts / Dent Update 10:261~273
ten Cate JM / 1991 / Mechanistic aspects of the interactions between fluoride and dental enamel / Crit Rev Oral Biol Med 2:283~296
Reynolds EC / 2008 / Fluoride and casein phosphopeptide-amorphous calcium phosphate / J Dent Res 87:344~348
Featherstone JD / 1993 / Effect of whole saliva components on enamel demineralization in vitro / Crit Rev Oral Biol Med 4:357~362
Silverstone LM / 1983 / Remineralization and enamel caries: new concepts / Dent Update 10:261~273
ten Cate JM / 1991 / Mechanistic aspects of the interactions between fluoride and dental enamel / Crit Rev Oral Biol Med 2:283~296
Reynolds EC / 2008 / Fluoride and casein phosphopeptide-amorphous calcium phosphate / J Dent Res 87:344~348
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