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자료유형
학술저널
저자정보
Fernando A M Herbella (Escola Paulista de Medicina Federal University of Sao Paulo Sao Paulo Brazil) Ramiro Colleoni (Escola Paulista de Medicina Federal University of Sao Paulo São Paulo Brazil) Luiz Bot (Escola Paulista de Medicina Federal University of Sao Paulo São Paulo Brazil) Fernando P P Vicentine (Escola Paulista de Medicina Federal University of Sao Paulo São Paulo Brazil) Marco G Patti (Department of Surgery University of Chicago Il Chicago USA)
저널정보
대한소화관운동학회(현 대한소화기능성질환.운동학회) Journal of Neurogastroenterology and Motility (JNM) Journal of Neurogastroenterology and Motility (JNM) Vol.22 No.2
발행연도
2016.1
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226 - 230 (5page)

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Background/AimsEndoscopic therapy for esophageal varices may lead to esophageal dysmotility. High-resolution manometry is probably the moreadequate tool to measure esophageal motility in these patients. This study aimed to evaluate esophageal motility using high resolutionmanometry following eradication of esophageal varices by endoscopic sclerotherapy. MethodsWe studied 21 patients (11 women, age 52 [45-59] years). All patients underwent eradication of esophageal varices with endoscopicsclerotherapy and subsequent high resolution manometry. ResultsA significant percentage of defective lower esophageal sphincter (basal pressure 14.3 [8.0-20.0] mmHg; 43% hypertonic) andhypocontractility (distal esophageal amplitude 50 [31-64] mmHg; proximal esophageal amplitude 40 [31-61] mmHg; distal contractileintegral 617 [403-920] mmHg∙sec∙cm; 48% ineffective) was noticed. Lower sphincter basal pressure and esophageal amplitudecorrelated inversely with the number of sessions (P < 0.001). No manometric parameter correlated with symptoms or intervalbetween last endoscopy and manometry. ConclusionsEsophageal motility after endoscopic sclerotherapy is characterized by: (1) defective lower sphincter and (2) defective and hypotensiveperistalsis. Esophageal dysmotility is associated to an increased number of endoscopic sessions, but manometric parameters do notpredict symptoms.

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