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논문 기본 정보

자료유형
학술저널
저자정보
Hyoungmin Kim (Orthopedic Surgery Seoul National University Hosp) 장삼열 (서울대학교병원) Jae Hong Ha (Orthopedic Surgery Seoul National University Hosp) 서상교 (서울아산병원) Bong-Soon Chang (Orthopedic Surgery Seoul National University Hosp) Choon-Ki Lee (Orthopedic Surgery Seoul National University Hosp)
저널정보
대한척추외과학회 Asian Spine Journal Asian Spine Journal Vol.12 No.5
발행연도
2018.1
수록면
919 - 926 (8page)

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Study Design: This was a retrospective cohort study. Purpose: We evaluated the predictive value of the Spinal Instability Neoplastic Score (SINS) system for spinal adverse events (SAEs) in patients with single spinal metastatic tumor. Overview of Literature: The SINS system was developed to assess spinal instability in patients with single metastatic spinal tumor. However, the system’s potential predictive value for SAEs has been partially studied. Methods: This system was applied to a retrospective cohort of 78 patients with single spinal metastatic tumors. The patients underwent surgical treatment and were postoperatively followed up for at least 2 years or until death. The attribution of each score and total SINS to SAE (vertebral compression fracture [VCF] and spinal cord compression [SCC]) occurrence was assessed using the Cox proportional hazards model. Results: SAEs occurred on average 7 months after diagnosis of spinal metastasis. The mean survival rate post diagnosis was 43 months. Multivariate analysis using the Cox proportional hazards model revealed that the pain (p =0.029) and spinal alignment (p =0.001) scores were significantly related to VCF occurrence, whereas the pain (p =0.008) and posterolateral involvement (p =0.009) scores were related to SCC occurrence. Conclusions: Among the components of the SINS system, while pain and spinal alignment showed a significant association with VCF occurrence, pain and posterolateral involvement showed association with SCC occurrence.

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