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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 706 - 714 (9page)
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Study Design: Prospective, cohort, non-inferiority study. Purpose: This study evaluated the clinical and radiological outcomes of interbody fusion using a combination of demineralized bone matrix (DBM) and hydroxyapatite (HA). Overview of Literature: The use of autografts remains a gold standard in lumbar interbody fusion, but the limited availability and donor site morbidity encourages the use of bone substitutes. In addition to autografts, a combination of HA and DBM is being increasingly use for lumbar interbody fusion. However, there are no data on the clinical and radiological outcomes of this procedure. Methods: We examined 35 patients with lumbar degenerative spondylolisthesis who underwent transforaminal interbody fusion. Autografts were used in 18 patients, and 17 patients received a combination of HA and DBM. Clinical outcomes were evaluated using the visual analog scale (VAS) for back and leg pain, Oswestry disability index (ODI), and Japanese Orthopaedic Association (JOA) scores at 3, 6, and 12 months postoperatively. Fusion was evaluated using computed tomography images obtained at 12 months postoperatively. Results: The mean ODI, JOA, and back and leg pain VAS scores increased significantly in both groups. However, the VAS, JOA, and ODI scores did not differ significantly between the two groups (p =0.599, p =0.543, and p =0.780, respectively). The fusion rates at 1 year postoperatively were 77.8% and 76.5% in the autograft and HA+DBM groups, respectively (p =0.99). Conclusions: The clinical and radiological outcomes of using a combination of HA and DBM in lumbar interbody fusion were not inferior to those of using autografts. A combination of HA and DBM can be considered as an alternative in patients with lumbar degenerative spondylolisthesis requiring surgery.
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참고문헌 (4)
참고문헌 신청
Young Seok Lee / 2014 / Comparison of Transforaminal Lumbar Interbody Fusion with Direct Lumbar Interbody Fusion : Clinical and Radiological Results / 대한신경외과학회지 56(6):469~474
Young Seok Lee / 2014 / Direct Lateral Lumbar Interbody Fusion : Clinical and Radiological Outcomes / 대한신경외과학회지 55(5):248~254
Hunt T / 2007 / Contralateral radiculopathy after transforaminal lumbar interbody fusion / Eur Spine J 16(Suppl 3):311~314
Kyoung-Min Jang / 2015 / Acute Contralateral Radiculopathy after Unilateral Transforaminal Lumbar Interbody Fusion / 대한신경외과학회지 58(4):350~356
Young Seok Lee / 2014 / Direct Lateral Lumbar Interbody Fusion : Clinical and Radiological Outcomes / 대한신경외과학회지 55(5):248~254
Hunt T / 2007 / Contralateral radiculopathy after transforaminal lumbar interbody fusion / Eur Spine J 16(Suppl 3):311~314
Kyoung-Min Jang / 2015 / Acute Contralateral Radiculopathy after Unilateral Transforaminal Lumbar Interbody Fusion / 대한신경외과학회지 58(4):350~356
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