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논문 기본 정보

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학술저널
저자정보
정종인 (계명대학교동산의료원) 이정주 (삼성서울병원) 김선우 (삼성생명과학연구소) 김수진 (성균관대학교 의과대학 삼성서울병원 이비인후과학교실) 홍상덕 (삼성서울병원) 정승규 (성균관대학교) 동헌종 (성균관대학교) 김호중 (삼성서울병원) 김효열 (성균관대학교)
저널정보
대한비과학회 Journal of Rhinology Journal of Rhinology Vol.23 No.1
발행연도
2016.1
수록면
6 - 16 (11page)

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Background and Objectives: Obstructive sleep apnea syndrome(OSAS) is characterized by repeated apnea, hypopnea, and micro-arousals during sleep. Among various treatment modalities of OSAS, continuous positive airway pressure(CPAP) treatment is the most effective and successful. The aim of this study was to compare efficacy and safety of newly developed Korean CPAP with standard CPAP in OSAS patients. Materials and Method: In total, 20 of 26 recruited OSAS patients completed the study. All subjects first used the standard CPAP for 4 weeks. After an at least 2 week wash-out period, the subjects used the newly developed CPAP for 4 weeks. Polysomnography, questionnaires associated with sleep, lipid profile, pulmonary function test, cardiac marker, and physical examinations were evaluated at baseline and were followed-up after each treatment. Results: After treatment with the newly developed CPAP, the apnea-hypopnea index was decreased from 53.2/hr to 2.5/hr and was equivalent to that of the standard CPAP. Most of the changes in questionnaire scores, laboratory findings, and physical examinations after newly developed CPAP treatment were equivalent to those with standard CPAP. No serious adverse events were observed during the study. Conclusion: The efficacy and safety of a newly developed CPAP are equivalent to those of standard CPAP in OSAS patients.

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