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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Purpose: Extracorporeal treatment has been used increasingly to treat patients with acute ethylene glycol poisoning. We analyzed all patients with acute poisoning of ethylene glycol during a recent 10-year period to provide clinical recommendations for adequate application of continuous renal replacement therapy for these patients. Methods: A retrospective chart review study was conducted for patients whose final diagnosis were “toxic effects of glycols or other alcohols,” between October 2006 and September 2016. The basal characteristics of patients, suspected amount of ingestion, intention of poisoning, concomitant alcohol ingestion, mental state at admission, time from exposure to admission, chief complaint, length of hospital stay, method of treatments, laboratory results including acute kidney injury and urine oxalate crystal, as well as treatment results were examined. Results: A total number of 14 patients were included in this study. Nine patients (64.3%) underwent continuous renal replacement therapy; 5 patients (35.7%) underwent ethanol mono-therapy. Between the antidote therapy group and the extracorporeal treatment group, there was a significant difference in the levels of plasma bicarbonate, chloride, anion gap, pH, and base excess in arterial blood gas analysis, as well as the calculated osmolar gap. One patient expired due to multi-organ failure, while the others recovered completely. Conclusion: Continuous renal replacement therapy was most frequently chosen as a treatment method in patients with acute ethylene glycol poisoning. Further research regarding indication of continuous renal replacement therapy and combing therapy with other treatment will be necessary to determine the best treatment method.
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참고문헌 (26)
참고문헌 신청
Brown CG / 1983 / Ethylene glycol poisoning / Ann Emerg Med 12:501~506
Linnanvuo-Laitinen M / 1986 / Ethylene glycol intoxication / J Toxicol Clin Toxicol 24:167~174
Turk J / 1986 / Ethylene glycol intoxication / Arch Intern Med 146:1601~1603
de Chazal L / 1999 / The ‘sweet killer’. Can you recognize the symptoms of ethylene glycol poisoning? / Postgrad Med 106:221~224
Barceloux DG / 1999 / American academy of clinical toxicology practice guidelines on the treatment of ethylene glycol poisoning / J Toxicol Clin Toxicol 37:537~560
Linnanvuo-Laitinen M / 1986 / Ethylene glycol intoxication / J Toxicol Clin Toxicol 24:167~174
Turk J / 1986 / Ethylene glycol intoxication / Arch Intern Med 146:1601~1603
de Chazal L / 1999 / The ‘sweet killer’. Can you recognize the symptoms of ethylene glycol poisoning? / Postgrad Med 106:221~224
Barceloux DG / 1999 / American academy of clinical toxicology practice guidelines on the treatment of ethylene glycol poisoning / J Toxicol Clin Toxicol 37:537~560
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