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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 226 - 233 (8page)
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초록· 키워드
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Purpose: The purpose of this study was to analyze the characteristics of initially missed andrebiopsy-detected prostate cancers following 12-core transrectal biopsy. Methods: A total of 45 patients with prostate cancers detected on rebiopsy and 45 patients withprostate cancers initially detected on transrectal ultrasound-guided biopsy were included in thestudy. For result analysis, the prostate was divided into six compartments, and the cancer positiverates, estimated tumor burden, and agreement rates between biopsy and surgical specimens,along with clinical data, were evaluated. Results: The largest mean tumor burden was located in the medial apex in both groups. Therewere significantly more tumors in this location in the rebiopsy group (44.9%) than in the controlgroup (30.1%, P=0.015). The overall sensitivity of biopsy was significantly lower in the rebiopsygroup (22.5% vs. 43.4%, P<0.001). The agreement rate of cancer positive cores betweenbiopsy and surgical specimens was significantly lower in the medial apex in the rebiopsy groupcompared with that of the control group (50.0% vs. 65.6%, P=0.035). The cancer positive ratesof target biopsy cores and premalignant lesions in the rebiopsy group were 63.1% and 42.3%,respectively. Conclusion: Rebiopsy-detected prostate cancers showed different spatial distribution and lowercancer detection rate of biopsy cores compared with initially diagnosed cancers. To overcomelower cancer detection rate, target biopsy of abnormal sonographic findings, premalignantlesions and medial apex which revealed larger tumor burden would be recommended when performing rebiopsy.
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참고문헌 (22)
참고문헌 신청
Verim L / 2013 / Impact of PSA and DRE on histologic findings at prostate biopsy in Turkish men over 75 years of age / Asian Pac J Cancer Prev 14:6085~6088
안재현 / 2014 / Nomogram for Prediction of Prostate Cancer with Serum Prostate Specific Antigen Less than 10 ng/mL / Journal of Korean Medical Science 29(3):338~342
Halpern EJ / 2000 / Using gray-scale and color and power Doppler sonography to detect prostatic cancer / AJR Am J Roentgenol 174:623~627
Salomon L / 1999 / Value of ultrasound-guided systematic sextant biopsies in prostate tumor mapping / Eur Urol 35:289~293
Taira AV / 2010 / Performance of transperineal template-guided mapping biopsy in detecting prostate cancer in the initial and repeat biopsy setting / Prostate Cancer Prostatic Dis 13:71~77
안재현 / 2014 / Nomogram for Prediction of Prostate Cancer with Serum Prostate Specific Antigen Less than 10 ng/mL / Journal of Korean Medical Science 29(3):338~342
Halpern EJ / 2000 / Using gray-scale and color and power Doppler sonography to detect prostatic cancer / AJR Am J Roentgenol 174:623~627
Salomon L / 1999 / Value of ultrasound-guided systematic sextant biopsies in prostate tumor mapping / Eur Urol 35:289~293
Taira AV / 2010 / Performance of transperineal template-guided mapping biopsy in detecting prostate cancer in the initial and repeat biopsy setting / Prostate Cancer Prostatic Dis 13:71~77
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