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학술저널
저자정보
Hyo-Shik Kim (순천향대학교 의과대학 서울병원 내과) 이경은 (Division of Nephrology Department of Internal Medicine Soon Chun Hyang University Seoul Korea) 오지현 (Division of Nephrology Department of Internal Medicine Soon Chun Hyang University Seoul Korea) 정찬성 (Division of Nephrology Department of Internal Medicine Soon Chun Hyang University Seoul Korea) Dughyun Choi (Division of Nephrology Department of Internal Medicine Soon Chun Hyang University Seoul Korea) Yunsuek Kim (Division of Nephrology Department of Internal Medicine Soon Chun Hyang University Seoul Korea) 전진석 (Division of Nephrology Department of Internal Medicine Soon Chun Hyang University Seoul Korea) 한동철 (순천향대학교) 노현진 (순천향대학교)
저널정보
대한신장학회 Kidney Research and Clinical Practice Kidney Research and Clinical Practice Vol.35 No.3
발행연도
2016.1
수록면
187 - 189 (3page)

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A 65-year-old man was transferred from the Department of Vascular Surgery to Nephrology because of cardiac arrest during hemodialysis. He underwent incision and drainage for treatment of a buttock abscess. Nafamostat mesilate was used as an anticoagulant for hemodialysis to address bleeding from the incision and drainage site. Sudden cardiac arrest occurred after 15 minutes of dialysis. The patient was treated in the intensive care unit for 5 days. Continuous veno-venous hemodiafiltration was started without any anticoagulant in the intensive care unit. Conventional hemodialysis was reinitiated, and nafamostat mesilate was used again because of a small amount of continued bleeding. Ten minutes after hemodialysis, the patient complained of anaphylactic signs and symptoms such as dyspnea, hypotension, and facial swelling. Epinephrine, dexamethasone, and pheniramin were injected under the suspicion of anaphylactic shock, and the patient recovered. Total immunoglobulin E titer was high, and skin prick test revealed weak positivity for nafamostat mesilate. We first report a case of anaphylactic shock caused by nafamostat mesilate in Korea.

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