지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 135 - 142 (8page)
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초록· 키워드
오류제보하기
Purpose: Changes in serum biomarkers of cardiac and muscle damage have been studied in ultra-marathon runners for distances up to 308 km. We investigated these biomarker changes following a 622-km super-ultramarathon race. Methods: A group of men with a mean age of 52.7±4.8 years participated. Blood samples were obtained pre-race, during the race, and post-race, to analyze the aforementioned biomarkers. Results: Creatine kinase and creatine kinase-MB (CK-MB) levels increased during the race, and both steadily declined post-race with CK-MB declining at a slower rate. Lactic acid dehydrogenase levels overall were increased over pre-race levels. White blood cell counts increased during the race. Red blood cell decreased from pre-race to 300 km and 622 km. Platelet increased only in the recovery period. High-sensitivity C-reactive protein levels were increased throughout the race and at day 3 compared to pre-race levels. Cardiac troponin I (cTnI) levels increased during the race. N-terminal pro b-type natriuretic peptide (NT-proBNP) levels increased during the race. Conclusion: The rise in cTnI was not clinically significant, and highly elevated NT-proBNP levels during the race indicates that myocardial burden rose linearly as running distance increased. However, no clinical risk was found as most of the markers returned to normal range during the recovery.
목차
등록된 정보가 없습니다.
참고문헌 (29)
참고문헌 신청
Fortescue EB / 2007 / Cardiac troponin increases among runners in the Boston Marathon / Ann Emerg Med 49:137~143
Sedaghat-Hamedani F / 2015 / Biomarker changes after strenuous exercise can mimic pulmonary embolism and cardiac injury: a metaanalysis of 45 studies / Clin Chem 61:1246~1255
Herrmann M / 2003 / Post-race kinetics of cardiac troponin T and I and N-terminal pro-brain natriuretic peptide in marathon runners / Clin Chem 49:831~834
Clarkson PM / 2007 / Exertional rhabdomyolysis and acute renal failure in marathon runners / Sports Med 37:361~363
Scharhag J / 2008 / Exercise-associated increases in cardiac biomarkers / Med Sci Sports Exerc 40:1408~1415
Sedaghat-Hamedani F / 2015 / Biomarker changes after strenuous exercise can mimic pulmonary embolism and cardiac injury: a metaanalysis of 45 studies / Clin Chem 61:1246~1255
Herrmann M / 2003 / Post-race kinetics of cardiac troponin T and I and N-terminal pro-brain natriuretic peptide in marathon runners / Clin Chem 49:831~834
Clarkson PM / 2007 / Exertional rhabdomyolysis and acute renal failure in marathon runners / Sports Med 37:361~363
Scharhag J / 2008 / Exercise-associated increases in cardiac biomarkers / Med Sci Sports Exerc 40:1408~1415
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