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논문 기본 정보

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학술저널
저자정보
Ahmet Goktug Ertem (Department of Cardiology Ataturk Training and Research Hospital Ankara) Filiz Ozcelik (Department of Cardiology Ataturk Training and Research Hospital AnkaraTurkey) Haci Ahmet Kasapkara (Department of Cardiology Yildirim Beyazit University Ankara Turkey) Cemal Koseoglu (Department of Cardiology Ataturk Training and Research Hospital AnkaraTurkey) Serdal Bastug (Department of Cardiology Ataturk Training and Research Hospital AnkaraTurkey) Huseyin Ayhan (Department of Cardiology Yildirim Beyazit University Ankara Turkey) Cenk Sari (Department of Cardiology Ataturk Training and Research Hospital AnkaraTurkey) Nihal Akar Bayram (Department of Cardiology Yildirim Beyazit University Ankara Turkey) Emine Bilen (Department of Cardiology Ataturk Training and Research Hospital AnkaraTurkey) Tahir Durmaz (Department of Cardiology Yildirim Beyazit University Ankara Turkey) Telat Keles (Department of Cardiology Yildirim Beyazit University Ankara Turkey) Engin Bozkurt (Department of Cardiology Yildirim Beyazit University Ankara Turkey)
저널정보
대한심장학회 Korean Circulation Journal Korean Circulation Journal Vol.46 No.6
발행연도
2016.1
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768 - 773 (6page)

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Background and Objectives: In this study, we examined the role of inflammatory parameters in an apical mural thrombus with a reduced ejection fraction due to large anterior myocardial infarction (MI). Subjects and Methods: A total of 103 patients who had suffered from heart failure, 45 of whom had left ventricular apical thrombus (AT) after a large anterior MI, were enrolled in the study. A detailed clinical history was taken of each participant, biochemical inflammatory markers, which were obtained during admission, were analyzed and an echocardiographical and angiographical evaluation of specific parameters were performed. Results: There were no statistically significant differences in terms of age, gender, and history of hypertension, diabetes mellitus, and atrial fibrillation between both groups (p>0.05). Similarly there were no statistically significant differences in terms of biochemical and echocardiographic parameters (p>0.05). However, there were significant differences in terms of neutrophil lymphocyte ratio (p=0.032). After a multivariate regression analysis, neutrophil lymphocyte ratio (NLR) was an independent predictor of thrombus formation (ß: 0.296, p=0.024). The NLR >2.74 had a 78% sensivity and 61% specifity in predicting thrombus in patients with a low left ventricular ejection fraction. Conclusion: In this study, neutrophil lymphocyte ratios were significantly higher in patients with apical thrombus.

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참고문헌 (26)

참고문헌 신청
Sharma ND / 2000 / Left ventricular thrombus and subsequent thromboembolism in patients with severe systolic dysfunction / Chest 117:314~320 google schola Schneider C / 2003 / Images in cardiovascular medicine. Unusual biventricular thrombus formation in acute myeloid leukemia and factor V Leiden mutation / Circulation 107:e114~e116 google schola Thomson SP / 1995 / Incremental value of the leukocyte differential and the rapid creatine kinase-MB isoenzyme for the early diagnosis of myocardial infarction / Ann Intern Med 122:335~341 google schola Delewi R / 2012 / Left ventricular thrombus formation after acute myocardial infarction / Heart 98:1743~1749 google schola Johannessen KA / 1987 / Increased occurrence of left ventricular thrombi during early treatment with timolol in patients with acute myocardial infarction / Circulation 75:151~155 google schola

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