지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 456 - 467 (12page)
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초록· 키워드
오류제보하기
Blood pressure (BP) exhibits different variabilities and surges with different time phases, from the shortest beat-by-beat to longest yearly changes. We hypothesized that the synergistic resonance of these BP variabilites generates an extraordinarily large dynamic surge in BP and triggers cardiovascular events (the resonance hypothesis). The power of pulses is transmitted to the peripheral sites without attenuation by the large arteries, in individuals with stiffened arteries. Thus, the effect of a BP surge on cardiovascular risk would be especially exaggerated in high-risk patients with vascular disease. Based on this concept, our group recently proposed a new theory of systemic hemodynamic atherothromboltic syndrome (SHATS), a vicious cycle of hemodynamic stress and vascular disease that advances organ damage and triggers cardiovascular disease. Clinical phenotypes of SHATS are large-artery atherothombotic diseases such as stroke, coronary artery disease, and aortic and pheripheral artery disease; small-artery diseases, and microcirculation-related disease such as vascular cognitive dysfunction, heart failure, and chronic kidney disease. The careful consideration of BP variability and vascular diseases such as SHATS, and the early detection and management of SHATS, will achieve more effective individualized cardiovascular protection. In the near future, information and communication technology-based ‘anticipation medicine’ predicted by the changes of individual BP values could be a promising approach to achieving zero cardiovascular events.
목차
등록된 정보가 없습니다.
참고문헌 (87)
참고문헌 신청
Lawes CM / 2003 / Blood pressure indices and cardiovascular disease in the Asia Pacific region: a pooled analysis / Hypertension 42:69~75
Ueshima H / 2008 / Cardiovascular disease and risk factors in Asia: a selected review / Circulation 118:2702~2709
Hoshide S / 2016 / Treatment considerations of clinical physician on hypertension management in Asia / Curr Hypertens Rev 12:164~168
Park JB / 2015 / Systolic hypertension: an increasing clinical challenge in Asia / Hypertens Res 38:227~236
Shimamoto K / 2014 / The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2014) / Hypertens Res 37:253~390
Ueshima H / 2008 / Cardiovascular disease and risk factors in Asia: a selected review / Circulation 118:2702~2709
Hoshide S / 2016 / Treatment considerations of clinical physician on hypertension management in Asia / Curr Hypertens Rev 12:164~168
Park JB / 2015 / Systolic hypertension: an increasing clinical challenge in Asia / Hypertens Res 38:227~236
Shimamoto K / 2014 / The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2014) / Hypertens Res 37:253~390
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