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자료유형
학술저널
저자정보
김현진 (Korea National Rehabilitation Research Institute) 윤석준 (고려대학교) 오인환 (Kyung Hee University College of Medicine) 임재희 (Kyung Hee University College of Medicine) Young Ae Kim (Cancer Policy Branch National Cancer Control Institute National Cancer Center Goyang)
저널정보
대한심장학회 Korean Circulation Journal Korean Circulation Journal Vol.46 No.3
발행연도
2016.1
수록면
384 - 393 (10page)

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Background and Objectives: In this retrospective cohort study, we sought to elucidate the relationship between medication adherence(MA) and the incidence of complications in patients with newly diagnosed hypertension. Subjects and Methods: Using claims data from the National Health Insurance Service, we measured health outcomes based on levels ofMA, analyzed the incidence of complications in patients with a good MA, and clarified factors that may affect or predict MA. Results: In 2008, a total of 4294773 patients were diagnosed with hypertension and were subsequently prescribed anti-hypertensivemedications. In the present study, we enrolled 564782 patients who met our inclusion/exclusion criteria. The 40-59% medicationpossession ratio (MPR) group had a 1.36 times higher risk of developing complications (95% confidence interval [CI]: 1.27-1.45) than didthe MPR≥ 80% group, as revealed through Cox’s proportional hazards analysis. Similarly, the <20% MPR group was 2.01 times more likelyto develop complications than the good MA group (95% CI: 1.82-2.23). Overall, patients who had a lower level of MA had a higher risk ofdeveloping complications. Conclusion: Our results demonstrate that MA is tightly correlated with hypertension health outcomes. Improving MA could be onestrategy for reducing the risk of cerebrovascular disease complications and the loss of productivity in these patients.

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