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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한비만학회 Journal of Obesity & Metabolic Syndrome Journal of Obesity & Metabolic Syndrome Vol.27 No.1
- 발행연도
- 2018.1
- 수록면
- 53 - 60 (8page)
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초록· 키워드
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Background: Vitamin D deficiency is known to increase the incidence of metabolic syndrome. Nonalcoholic fatty liver disease is a common metabolic disease in patients with type 2 diabetes. This study evaluated nonalcoholic fatty liver disease and abdominal fat accumulation according to 25-hydroxyvitamin D status in patients with type 2 diabetes. Methods: The study comprised 302 patients with type 2 diabetes. Patients were divided into three groups based upon their 25-hydroxyvitamin D status: vitamin D deficient group (<10 ng/mL), vitamin D insufficient group (≥10 to <20 ng/mL) and vitamin D sufficient group (≥20 ng/mL). Patient clinical and laboratory markers were evaluated retrospectively. Results: Visceral fat thickness was significantly higher in the vitamin D deficient group. There were no differences in glycemic control, body mass index, and subcutaneous fat thickness correlated with 25-hydroxyvitamin D status. The prevalence of nonalcoholic fatty liver disease was significantly higher in the vitamin D deficient group compared to the vitamin D sufficient and vitamin D insufficient groups. In multivariate logistic analysis, after adjustment for age, sex, body mass index, glycated hemoglobin and homeostasis model assessment of insulin resistance, patients with type 2 diabetes in the vitamin D sufficient group showed significantly lower odds ratio for nonalcoholic fatty liver disease than those within the vitamin D deficient group. Conclusion: In type 2 diabetes, the vitamin D deficient group showed thicker visceral fat thickness and higher nonalcoholic fatty liver disease prevalence.
목차
등록된 정보가 없습니다.
참고문헌 (38)
참고문헌 신청
Poole KE / 2006 / Reduced vitamin D in acute stroke / Stroke 37:243~245
Giovannucci E / 2008 / 25-Hydroxyvitamin D and risk of myocardial infarction in men: a prospective study / Arch Intern Med 168:1174~1180
Giovannucci E / 2006 / Prospective study of predictors of vitamin D status and cancer incidence and mortality in men / J Natl Cancer Inst 98:451~459
Jenab M / 2010 / Association between pre-diagnostic circulating vitamin D concentration and risk of colorectal cancer in European populations: a nested case-control study / BMJ 340:b5500
Ginde AA / 2009 / Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey / Arch Intern Med 169:384~390
Giovannucci E / 2008 / 25-Hydroxyvitamin D and risk of myocardial infarction in men: a prospective study / Arch Intern Med 168:1174~1180
Giovannucci E / 2006 / Prospective study of predictors of vitamin D status and cancer incidence and mortality in men / J Natl Cancer Inst 98:451~459
Jenab M / 2010 / Association between pre-diagnostic circulating vitamin D concentration and risk of colorectal cancer in European populations: a nested case-control study / BMJ 340:b5500
Ginde AA / 2009 / Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey / Arch Intern Med 169:384~390
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