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자료유형
학술저널
저자정보
정명규 (한국원자력의학원) 신의섭 (한국원자력의학원) 기영준 (한국원자력의학원) 김영배 (한국원자력의학원) 문선미 (한국원자력의학원) 성세진 (한국원자력의학원)
저널정보
대한대장항문학회 Annals of Coloproctology Annals of Coloproctolgy Vol.33 No.6
발행연도
2017.1
수록면
210 - 218 (9page)

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Purpose: In this study, we investigated both the characteristics of right colon cancer (RTCC) in comparison with those of left colon cancer (LTCC) and the impact of the location of the colon cancer on the prognosis. Methods: We retrospectively analyzed the cases of 974 patients with nonmetastatic colon cancer who had undergone surgery with a curative intent from January 2001 to December 2011. RTCC was defined as a tumor located proximal to the splenic flexure. The characteristics of RTCC cancer were investigated by using descriptive analyses, and their impacts on the prognosis were assessed by using a Cox multivariate regression. Results: Compared to LTCC, RTCC showed a female-dominant feature, and an undifferentiated pathology was more frequently observed. The number of lymph nodes retrieved from patients with RTCC was significantly higher than that retrieved from patients with LTCC. During 75 months of follow-up, peritoneal recurrence was more common in patients with RTCC than it was in patients with LTCC, and among the patients with stage III colon cancer, the disease-free and the overall survival rates were significantly worse in patients with RTCC. After adjustments with the other prognostic factors associated with colon cancer had been made, a tumor located at the right colon was found to be independently associated with poor prognosis. Conclusion: RTCC showed unique clinicopathologic features and was associated with a poorer prognosis.

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