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논문 기본 정보

자료유형
학술저널
저자정보
Wann Jia Loh (Changi General Hospital) Dawn Shao Ting Lim (Singapore General Hospital) Lih Ming Loh (Singapore General Hospital) Peng Chin Kek (Singapore General Hospital)
저널정보
대한내분비학회 Endocrinology and Metabolism Endocrinology and Metabolism Vol.33 No.3
발행연도
2018.1
수록면
355 - 363 (9page)

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Background: The aim of this study was to investigate the factors associated with resolution of hypertension after adrenalectomy inpatients with primary aldosteronism. A secondary aim was to describe our use of the contralateral ratio in adrenal venous sampling(AVS) in the setting of suboptimal successful cannulation rates. Methods: A retrospective review of patients who underwent AVS followed by unilateral adrenalectomy for primary aldosteronismwas performed. Results: Complete resolution of hypertension and hypokalemia was seen in 17 of 40 patients (42.5%), while a clinical improvementin hypertension was seen in 38 of 40 (95%). Shorter duration of hypertension, mean aldosteronoma resolution score (ARS), and ahigh ARS of 3 to 5 were associated with resolution of hypertension after adrenalectomy (P=0.02, P=0.02, and P=0.004, respectively). Of the individual components of ARS, only a duration of hypertension of ≤6 years was associated with resolution of hypertensionafter adrenalectomy (P=0.03). Conclusion: A shorter duration of hypertension was significantly associated with resolution of hypertension after adrenalectomy inpatients with primary aldosteronism.

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