메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
김민경 (서울대학교병원) 정혜승 (서울대학교병원) 곽수현 (서울대학교) 조영민 (서울대학교) 박경수 (서울대학교 의과대학) 김성연 (서울대학교)
저널정보
대한내분비학회 Endocrinology and Metabolism Endocrinology and Metabolism Vol.31 No.2
발행연도
2016.1
수록면
284 - 291 (8page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Background: The identification of a marker for hypoglycemia could help patients achieve strict glucose control with a lower riskof hypoglycemia. 1,5-Anhydro-D-glucitol (1,5-AG) reflects postprandial hyperglycemia in patients with well-controlled diabetes,which contributes to glycemic variability. Because glycemic variability is related to hypoglycemia, we aimed to evaluate thevalue of 1,5-AG as a marker of hypoglycemia. Methods: We enrolled 18 adults with type 2 diabetes mellitus (T2DM) receiving insulin therapy and assessed the occurrence ofhypoglycemia within a 3-month period. We measured 1,5-AG level, performed a survey to score the severity of hypoglycemia,and applied a continuous glucose monitoring system (CGMS). Results: 1,5-AG was significantly lower in the high hypoglycemia-score group compared to the low-score group. Additionally,the duration of insulin treatment was significantly longer in the high-score group. Subsequent analyses were adjusted by the durationof insulin treatment and mean blood glucose, which was closely associated with both 1,5-AG level and hypoglycemia risk. In adjusted correlation analyses, 1,5-AG was negatively correlated with hypoglycemia score, area under the curve at 80 mg/dL,and low blood glucose index during CGMS (P=0.068, P=0.033, and P=0.060, respectively). Conclusion: 1,5-AG level was negatively associated with hypoglycemia score determined by recall and with documented hypoglycemiaafter adjusting for mean glucose and duration of insulin treatment. As a result, this level could be a marker of the risk ofhypoglycemia in patients with well-controlled T2DM receiving insulin therapy.

목차

등록된 정보가 없습니다.

참고문헌 (28)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0