지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 825 - 834 (10page)
이용수
초록· 키워드
오류제보하기
Porcine epidemic diarrhea virus (PEDV), the causative agent of porcine epidemic diarrhea (PED), has led to tremendous economic losses in the global swine industry. Although the phylogeny of PEDV has been investigated extensively at the molecular level, there was no time-calibrated phylogenomic study on the virus. To improve insight into this topic, we analyzed 138 published genome sequences using the Bayesian coalescent analyses as well as Bayesian inferences and maximum likelihood methods. All of the global PEDV isolates were divided into six groups, except for one unclassified isolate. Of the six groups, Groups 1–5 comprised pandemic viruses while the remaining Group 6 contained classical isolates. Interestingly, the two clades, both pandemic and classical, consisted of clade-specific amino acid sequences in five genes: ORF1a, ORF1b, S, ORF3, and N. Within the pandemic clade, Group 1 and Group 2 originated from North America, whereas Group 3–Group 5 were derived from Asia. In Group 2, there was a common origin of S INDEL isolates. Within each group, there was no apparent association between temporal or geographic origin and heterogeneity of PEDVs. Our findings also showed that the PEDV virus evolved at a rate of 3.38 × 10−4 substitutions/site/year, and the most recent common ancestor of the virus emerged 75.9 years ago. Our Bayesian skyline plot analysis indicated that the PEDV had maintained constant effective population size excluding only a short period, around 2012, when a valley shaped decline in the effective number of infections occurred.
목차
등록된 정보가 없습니다.
참고문헌 (68)
참고문헌 신청
Bouckaert R / 2014 / BEAST 2: a software platform for Bayesian evolutionary analysis / PLoS Comput Biol 10:e1003537
Chen J-F / 2008 / Molecular characterization and phylogenetic analysis of membrane protein genes of porcine epidemic diarrhea virus isolates in China / Virus Genes 36:355~364
Chen Q / 2014 / Isolation and characterization of porcine epidemic diarrhea viruses associated with the 2013 disease outbreak among swine in the United States / J Clin Microbiol 52:234~243
Chen Q / 2016 / Pathogenesis comparison between the United States porcine epidemic diarrhoea virus prototype and S-INDELvariant strains in conventional neonatal piglets / J Gen Virol 97:1107~1121
Chiou M-T / 2014 / Molecular characterization of the porcine epidemic diarrhea virus TW4/2014 in Taiwan / Austin Virol Retrovirology 1:4
Chen J-F / 2008 / Molecular characterization and phylogenetic analysis of membrane protein genes of porcine epidemic diarrhea virus isolates in China / Virus Genes 36:355~364
Chen Q / 2014 / Isolation and characterization of porcine epidemic diarrhea viruses associated with the 2013 disease outbreak among swine in the United States / J Clin Microbiol 52:234~243
Chen Q / 2016 / Pathogenesis comparison between the United States porcine epidemic diarrhoea virus prototype and S-INDELvariant strains in conventional neonatal piglets / J Gen Virol 97:1107~1121
Chiou M-T / 2014 / Molecular characterization of the porcine epidemic diarrhea virus TW4/2014 in Taiwan / Austin Virol Retrovirology 1:4
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Pathogenicity and Viral Distribution of Wild Type Porcine Epidemic Diarrhea Virus and Its Cell Culture Adapted Porcine Epidemic Diarrhea Virus
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2022 .09
-
Antiviral Activity of Corylus heterophylla Fisch Against Porcine Epidemic Diarrhea Virus Infection
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2016 .09
-
Surface-Displayed Porcine IFN-λ3 in Lactobacillus plantarum Inhibits Porcine Enteric Coronavirus Infection of Porcine Intestinal Epithelial Cells
Journal of Microbiology and Biotechnology
2020 .01
-
ORF5a Protein of Porcine Reproductive and Respiratory Syndrome Virus is Indispensable for Virus Replication
한국미생물·생명공학회지
2015 .01
-
The Plant Cellular Systems for Plant Virus Movement
The Plant Pathology Journal
2017 .06
-
Pathogenicity of Clade 2.3.4.4 B H5N6 Highly Pathogenic Avian Influenza Viruses Isolated during 2017/2018 Winter Season in South Korea
한국미생물학회 학술대회논문집
2020 .10
-
Development of a Multiplex Polymerase Chain Reaction Assay for Detecting Five Previously Unreported Papaya Viruses for Quarantine Purposes in Korea
Research in Plant Disease(식물병연구)
2024 .09
-
Identification of a novel plant RNA virus species of the genus Amalgavirus in the family Amalgaviridae from chia (Salvia hispanica)
Genes & Genomics
2019 .01
-
Identification of Leonurus sibiricus as a Weed Reservoir for Three Pepper-Infecting Viruses
The Plant Pathology Journal
2016 .02
-
Molecular Characterization of an Isolate of Bean Common Mosaic Virus First Identified in Gardenia Using Metatranscriptome and Small RNA Sequencing
The Plant Pathology Journal
2024 .02
-
The Complete Genome Sequence of Fowlpox Virus Isolated in South Korea
한국미생물학회 학술대회논문집
2020 .10
-
Comprehensive Metatranscriptomic Analysis of Plant Viruses in Imported Frozen Cherries and Blueberries
The Plant Pathology Journal
2024 .08
-
Post-pandemic influenza A (H1N1) virus detection by real-time PCR and virus isolation
미생물학회지
2019 .03
-
Identification of Plant Viruses Infecting Pear Using RNA Sequencing
The Plant Pathology Journal
2021 .06
-
Application of Diagnostic Microarray Technique in Subtyping and Pathotyping of Avian Influenza Viruses Isolated in Mongolia
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2016 .03
-
Emergence of Viruses, Mechanisms and Recent Examples
한국미생물학회 학술대회논문집
2015 .04
-
Genome-Based Virus Taxonomy with the ICTV Database Extension
Genomics & informatics
2018 .01
-
Structure and Function of the Influenza A Virus Non-Structural Protein 1
Journal of Microbiology and Biotechnology
2019 .01
-
Present Status and Future Management Strategies for Sugarcane Yellow Leaf Virus: A Major Constraint to the Global Sugarcane Production
The Plant Pathology Journal
2020 .12
-
Genetic Characterization of an Ancestral Strain of the Avian-Origin H3N2 Canine Influenza Virus Currently Circulating in East Asia
Journal of Microbiology and Biotechnology
2016 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0