지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 502 - 507 (6page)
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초록· 키워드
오류제보하기
Maximal whole body exercise leads skeletal muscle blood flow to markedly increase to match metabolic demands, a phenomenon termed exercise hyperaemia that is accomplished by increasing vaso-dilation. However, local vasodilatory mechanisms in response to skele-tal muscle contraction remain uncertain. This review highlights meta-bolic vasodilators released from contracting skeletal muscle, endotheli-um, or blood cells. As a considerable skeletal muscle vasodilation po-tentially results in hypotension, sympathetic nerve activity needs to be augmented to elevate cardiac output and blood pressure during dy-namic exercise. However, since the enhanced sympathetic vasocon-striction restrains skeletal muscle blood flow, intramuscular arteries have an indispensable ability to blunt sympathetic activity for exercise hyperaemia. In addition, we discuss that mechanical compression of the intramuscular vasculature contributes to causing the initial phase of increasing vasodilation following a single muscle contraction. We have also chosen to focus on conducted (or ascending) electrical signals that evoke vasodilation of proximal feed arteries to elevate blood flow in the microcirculation of skeletal muscle. Endothelial hyperpolarization originating within distal arterioles ascends into the proximal feed arter-ies, thereby increasing total blood flow in contracting skeletal muscle. This brief review summarizes molecular mechanisms underlying the regulation of skeletal muscle blood flow to a single or sustained muscle contraction.
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등록된 정보가 없습니다.
참고문헌 (55)
참고문헌 신청
Armstrong ML / 2007 / Potassium initiates vasodilatation induced by a single skeletal muscle contraction in hamster cremaster muscle / J Physiol 581(Pt 2):841~852
Bagher P / 2011 / Regulation of blood flow in the microcirculation: role of conducted vasodilation / Acta Physiol (Oxf) 202:271~284
Ballard RE / 1998 / Leg intramuscular pressures during locomotion in humans / J Appl Physiol (1985) 84:1976~1981
Brock RW / 1998 / Effects of acetylcholine and nitric oxide on forearm blood flow at rest and after a single muscle contraction / J Appl Physiol (1985) 85:2249~2254
Calbet JA / 2012 / Skeletal muscle vasodilatation during maximal exercise in health and disease / J Physiol 590:6285~6296
Bagher P / 2011 / Regulation of blood flow in the microcirculation: role of conducted vasodilation / Acta Physiol (Oxf) 202:271~284
Ballard RE / 1998 / Leg intramuscular pressures during locomotion in humans / J Appl Physiol (1985) 84:1976~1981
Brock RW / 1998 / Effects of acetylcholine and nitric oxide on forearm blood flow at rest and after a single muscle contraction / J Appl Physiol (1985) 85:2249~2254
Calbet JA / 2012 / Skeletal muscle vasodilatation during maximal exercise in health and disease / J Physiol 590:6285~6296
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