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논문 기본 정보

자료유형
학술저널
저자정보
전혜지 (순천향대학교) 민지원 (순천향대학교) 김덕경 (순천향대학교) 서희경 (순천향대학교) 김선경 (순천향대학교) 김윤숙 (순천향대학교)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.33 No.34
발행연도
2018.1
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1 - 11 (11page)

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초록· 키워드

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Background: Many women with endometriosis have become pregnant through assisted reproductive technology (ART), and have often experienced placenta previa (PP) during pregnancy. The objective of this study was to assess the association between women with endometriosis, especially those who conceived with ART, and the risk of PP. Methods: Two reviewers independently determined studies that were considered suitable for meta-analyses published in various medicine-related databases from March 1, 2004 through July 31, 2017 without language restrictions. Eight studies met the inclusion criteria, with a combined sample size of 21,930 women. Of these 21,930 pregnancies, 6,256 had endometriosis (endometriosis) and 15,674 had no endometriosis. Four of these studies included 8,161 women who conceived with ART, 1,640 of whom had endometriosis (endometriosis + ART), and 6,521 of whom did not have endometriosis. Meta-analyses were estimated with odds ratios (ORs) and 95% confidence intervals (CIs) using random effect analysis according to heterogeneity of studies. Results: These meta-analyses showed women with endometriosis (endometriosis) have an increased risk of PP (OR, 4.038; 95% CI, 2.291–7.116; P = 0.000). These results showed women who conceived with ART (endometriosis + ART), have a substantially increased risk of PP (OR, 5.543; 95% CI, 1.659–18.523; P = 0.005). Conclusion: These meta-analyses demonstrate women with endometriosis have an increased risk of PP.

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