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논문 기본 정보

자료유형
학술저널
저자정보
Kim Kyong Young (Gyeongsang National University Changwon Hospital) 정승욱 (경상대학교) Yoon Changhyo (Gyeongsang National University Changwon Hospital) Jeong Heejeong (Gyeongsang National University Changwon Hospital) 조은빈 (경상대학교) 양태원 (경상대학교) Kim Seung Joo (Gyeongsang National University Changwon Hospital) Hwang Sean (Gyeongsang National University Changwon Hospital) 박기종 (경상대학교)
저널정보
대한신경집중치료학회 Journal of Neurocritical Care Journal of Neurocritical Care Vol.13 No.2
발행연도
2020.1
수록면
123 - 127 (5page)

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Background: Choriocarcinoma is a subtype of gestational trophoblastic disease (GTD) that can spread to multiple organs, including the central nervous system. Most cases of GTD affecting the central nervous system can cause intra- or extra-axial hemorrhages. Herein, we describe a rare case of multiple embolic infarctions and intracranial hemorrhages in a patient with GDT. Case Report: A 36-year-old woman with sudden headache and right homonymous hemianopsia was admitted to our hospital 19 hours from symptom onset. Brain magnetic resonance imaging revealed small acute infarctions in the territories of the left posterior cerebral artery and both middle cerebral arteries. Furthermore, intracerebral hemorrhage in the left occipital lobe, small amounts of intraventricular hemorrhage, and subarachnoid hemorrhage were observed. In the past, she gave birth to her child through cesarean section 6 months ago. D-dimer level was elevated with a value of 1.61 μg/mL (reference range <0.5 μg/mL). Her urine beta-human chorionic gonadotropin (hCG) was positive, and her serum beta-hCG level was >1,000 IU/mL. She was diagnosed with GTD and underwent chemotherapy. Conclusion: The precise pathogenesis of the coexistence of multiple embolic infarctions and intracranial hemorrhage remains unclear. Cancer-related coagulopathy, micro-tumor emboli, or both could be involved in the pathogenesis of the rare presentation of this patient.

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