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논문 기본 정보

자료유형
학술저널
저자정보
김선희 (Pusan National University Hospital) Sung Jin Park (Pusan National University Hospital) Chan Ik Park (Pusan National University Hospital) Seon Uoo Choi (Pusan National University Hospital) 김재훈 (부산대학교)
저널정보
대한외상중환자외과학회 Journal of Acute Care Surgery Journal of Acute Care Surgery Vol.9 No.2
발행연도
2019.1
수록면
72 - 75 (4page)

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Acquired hemophilia A (AHA) is a rare disease where typically coagulation factor VIII is inhibited by autoantibodies. It occurs in patients with no personal or familial history of bleeding. In this case study a 61-year-old male presented with a huge psoas hematoma. He had no history of bleeding disorders. He was initially diagnosed with delayed traumatic hematoma. Despite conservative and surgical treatments, coagulopathy was not resolved and postoperative bleeding continued. Consequently, coagulation factor tests were performed and showed reduced activity of factor VIII (2.7%). In addition, factor VIII inhibitor was detected. The patient was diagnosed with AHA and administered recombinant factor VIII for 3 days which resulted in the cessation of bleeding. AHA can lead to a life-threatening hemorrhage, and needs to be considered in differential diagnoses in any patients presenting with unexplained and repeated bleeding, where there is no personal or familial history of bleeding disorders.

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