지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Objective ： The combined use of benzodiazepines and opioids is associated with an increased risk of severe side effects. The purpose of this study was to investigate how often both drugs were prescribed simultaneously in the outpatient settings in Korea. Methods ： This study used data from the Korea Health Insurance Review and Assessment Service-National Patient Sample (HIRA-NPS) 2013-2018. We included a total of 6,932,776 individuals and detected a total of 73,697,937 physician office visits among them. The annual co-prescription (of benzodiazepines and opioids) visits rates (the number of physician office visits per 100 adults) and also the co-prescription percentages were analyzed. Results ： We found an average of 7.5 concomitant prescription visits per 100 adults throughout the six-year study. The rates decreased consistently from 9.0 in 2013 to 6.0 in 2018 with an annual percentage change (APC) of -8.5 [-10.1, -6.8] (95% confidence interval). The opioids were co-prescribed in 14.2% of visits in which benzodiazepine was prescribed. The percentage also decreased from 14.7% in 2013 to 13.1% in 2018, with an APC of -2.6% [-4.2, -1.0]. Conclusion : Our results suggest that benzodiazepines and opioids co-prescription decreased significantly in Korea’s outpatient settings recently based on the HIRA data.
목차
등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Page CP / 2002 / Integrated pharmacology / Mosby :671
Hollister LE / 1983 / The pre-benzodiazepine era / J Psychoactive Drugs 15:9~13
Bachhuber MA / 2016 / Increasing benzodiazepine prescriptions and overdose mortality in the United States, 1996-2013 / Am J Public Health 106:686~688
Windle A / 2007 / Benzodiazepine prescribing in elderly Australian general practice patients / Aust N Z J Public Health 31:379~381
Jones CM / 2015 / Emergency department visits and overdose deaths from combined use of opioids and benzodiazepines / Am J Prev Med 49:493~501
Hollister LE / 1983 / The pre-benzodiazepine era / J Psychoactive Drugs 15:9~13
Bachhuber MA / 2016 / Increasing benzodiazepine prescriptions and overdose mortality in the United States, 1996-2013 / Am J Public Health 106:686~688
Windle A / 2007 / Benzodiazepine prescribing in elderly Australian general practice patients / Aust N Z J Public Health 31:379~381
Jones CM / 2015 / Emergency department visits and overdose deaths from combined use of opioids and benzodiazepines / Am J Prev Med 49:493~501
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