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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 43 - 51 (9page)
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The aim of our study was to investigate whether high β-glucan-containing barley (7.2 g per 100 g) improves postprandial plasma glucose levels and suppresses postprandial insulin levels during a meal tolerance test in type 2 diabetic patients. A meal tolerance test (500 kcal) was conducted using two types of test meals: a test meal with white rice (WR) alone (WR diet) and a test meal with WR mixed with 50% barley (BR diet) as staple food. The side dish was the same in the both meals. The changes in plasma glucose and serum C-peptide immunoreactivity (CPR) levels for 180 minutes after ingestion of the test meals were compared. Ten patients with type 2 diabetes (age 52.5 ± 15.1 years, and 7 males and 3 females) were included in this study. The mean HbA1c level and body mass index were 8.8 ± 1.4%, and 29.7 ± 4.5 kg/m2, respectively. Plasma glucose levels after ingestion of the WR diet or BR diet peaked at 60 minutes, which showed no significant differences between the two types of test meals. However, the incremental area under the curve (IAUC) of plasma glucose levels after ingestion of BR diet was significantly lower than that of WR diet. The serum CPR levels at 180 min and their IAUC over 180 minutes after ingestion of BR diet were significantly lower than those of WR diet. Conclusion: Increase in postprandial plasma glucose and insulin levels was suppressed by mixing high-β-glucan barley with WR in type 2 diabetic patients.
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참고문헌 (33)
참고문헌 신청
International Diabetes Federation / IDF diabetes atlas-8th edition
Mukai N / 2014 / Trends in the prevalence of type 2 diabetes and prediabetes in community-dwelling Japanese subjects : The Hisayama Study / J Diabetes Investig 5:162~169
DeFronzo RA / 1991 / Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease / Diabetes Care 14:173~194
Katakami N / 2018 / Mechanism of development of atherosclerosis and cardiovascular disease in diabetes mellitus / J Atheroscler Thromb 25:27~39
Kato M / 2015 / Diagnosed diabetes and premature death among middle-aged Japanese: results from a large-scale population-based cohort study in Japan (JPHC study) / BMJ Open 5:e007736
Mukai N / 2014 / Trends in the prevalence of type 2 diabetes and prediabetes in community-dwelling Japanese subjects : The Hisayama Study / J Diabetes Investig 5:162~169
DeFronzo RA / 1991 / Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease / Diabetes Care 14:173~194
Katakami N / 2018 / Mechanism of development of atherosclerosis and cardiovascular disease in diabetes mellitus / J Atheroscler Thromb 25:27~39
Kato M / 2015 / Diagnosed diabetes and premature death among middle-aged Japanese: results from a large-scale population-based cohort study in Japan (JPHC study) / BMJ Open 5:e007736
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