지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Background: Neuropathic pain presents a therapeutic challenge because patients cannot be relieved from it, even when all known medical options have been tried. Several treatment guidelines have been provided, and several pharmacotherapies have been proposed with non-pharmacological treatments. This study aimed to present the current pharmacological and non-pharmacological treatments used to treat patients with neuropathic pain. Furthermore, several treatment guidelines for neuropathic pain are compared. Current Concepts: Tricyclic antidepressants, gabapentinoids, and serotonin-norepinephrine reuptake inhibitors are the first-line agents recommended by clinical guidelines in several countries. Tramadol and topical agents are recommended as second-line agents. Opioids and cannabinoids are recommended as third-line agents; cannabinoids are recommended by Canadian treatment guidelines. Combination therapy may be more effective because it results in synergistic pain-relieving effects, and the individual drug dose may be lower. Non-pharmacologic treatment is recommended as third-line or supplementary management because of the lack of evidence. Discussion and Conclusion: Several guidelines have recommended similar drugs; however, it is impossible to completely cure neuropathic pain. Therefore, therapeutic goals must be realistically discussed to improve patient compliance. In addition, additional studies based on pathophysiological mechanisms should be conducted to improve the management of neuropathic pain.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Treede RD / 2008 / Neuropathic pain : redefinition and a grading system for clinical and research purposes / Neurology 70:1630~1635
Sumitani M / 2018 / Executive summary of the clinical guidelines of pharmacotherapy for neuropathic pain : second edition by the Japanese Society of Pain Clinicians / J Anesth 32:463~478
Schlereth T / 2020 / Guideline"diagnosis and non interventional therapy of neuropathic pain"of the German Society of Neurology(deutsche Gesellschaft fur Neurologie) / Neurol Res Pract 2:16
Baron R / 2017 / Peripheral neuropathic pain : a mechanism-related organizing principle based on sensory profiles / Pain 158:261~272
Moisset X / 2020 / Pharmacological and non-pharmacological treatments for neuropathic pain: systematic review and French recommendations / Rev Neurol(Paris) 176:325~352
Sumitani M / 2018 / Executive summary of the clinical guidelines of pharmacotherapy for neuropathic pain : second edition by the Japanese Society of Pain Clinicians / J Anesth 32:463~478
Schlereth T / 2020 / Guideline"diagnosis and non interventional therapy of neuropathic pain"of the German Society of Neurology(deutsche Gesellschaft fur Neurologie) / Neurol Res Pract 2:16
Baron R / 2017 / Peripheral neuropathic pain : a mechanism-related organizing principle based on sensory profiles / Pain 158:261~272
Moisset X / 2020 / Pharmacological and non-pharmacological treatments for neuropathic pain: systematic review and French recommendations / Rev Neurol(Paris) 176:325~352
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