지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 119 - 125 (7page)
이용수
초록· 키워드
오류제보하기
Whipple disease is a systemic chronic infection caused by <i>Tropheryma whipplei</i>. Although chronic diarrhea is a common gastrointestinal symptom, diagnosis is often difficult because there are no specific endoscopic findings, and the pathogen is not detectable by stool culture. We present a female patient with Whipple disease who developed chronic bloody diarrhea and growth retardation at the age of 4 years. Colonoscopy showed a mildly edematous terminal ileum and marked erythema without vascular patterns throughout the sigmoid colon and rectum. Subsequently, a primary diagnosis of ulcerative colitis was made. Histopathological analysis of the terminal ileum showed the presence of foamy macrophages filled with periodic acidSchiff-positive particles. Polymerase chain reaction using DNA from a terminal ileum biopsy sample amplified a fragment of 16S rRNA from <i>T. whipplei</i>. Antibiotic treatment relieved the patient’s symptoms. There was no evidence of immunodeficiency in the present case. Since Whipple disease worsens after anti-tumor necrosis factor inhibitor therapy, considering this infection in the differential diagnosis may be important in patients with inflammatory bowel disease, especially before initiation of immunotherapy.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Benchimol EI / 2011 / Epidemiology of pediatric inflammatory bowel disease : a systematic review of international trends / Inflamm Bowel Dis 17:423~439
IBD Working Group of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition / 2005 / Inflammatory bowel disease in children and adolescents: recommendations for diagnosis: the Porto criteria / J Pediatr Gastroenterol Nutr 41:1~7
Yardley JH / 1961 / Combined electron and light microscopy in Whipple’s disease: demonstration of “bacillary bodies”in the intestine / Bull Johns Hopkins Hosp 109:80~98
Yajima N / 2013 / Whipple disease diagnosed with PCR using formalin-fixed paraffin-embedded specimens of the intestinal mucosa / Intern Med 52:219~222
Yogi T / 2004 / Whipple’s disease : the first Japanese case diagnosed by electron microscopy and polymerase chain reaction / Intern Med 43:566~570
IBD Working Group of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition / 2005 / Inflammatory bowel disease in children and adolescents: recommendations for diagnosis: the Porto criteria / J Pediatr Gastroenterol Nutr 41:1~7
Yardley JH / 1961 / Combined electron and light microscopy in Whipple’s disease: demonstration of “bacillary bodies”in the intestine / Bull Johns Hopkins Hosp 109:80~98
Yajima N / 2013 / Whipple disease diagnosed with PCR using formalin-fixed paraffin-embedded specimens of the intestinal mucosa / Intern Med 52:219~222
Yogi T / 2004 / Whipple’s disease : the first Japanese case diagnosed by electron microscopy and polymerase chain reaction / Intern Med 43:566~570
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Can Anti-Tumor Necrosis Factor Agents Be Discontinued in Patients with Inflammatory Bowel Disease?
Gut and Liver
2021 .09
-
Depressive Symptoms and Quality of Life in the Patients of Inflammatory Bowel Disease
Gut and Liver
2017 .07
-
Precision medicine in inflammatory bowel diseases
Intestinal research
2024 .01
-
Disability Index as a New Outcome Measure in Patients with Inflammatory Bowel Disease
Gut and Liver
2017 .01
-
Chemoprevention of Colitis-Associated Dysplasia or Cancer in Inflammatory Bowel Disease
Gut and Liver
2022 .11
-
염증장질환의 치료: 생물학적제제 및 새로운 치료법을 중심으로
대한의사협회지
2021 .09
-
Benign Colorectal Disease 2 : Inflammatory Bowel Disease
대한외과학회 학술대회 초록집
2015 .11
-
Benign Colorectal Disease 2 : Inflammatory Bowel Disease
대한외과학회 학술대회 초록집
2016 .11
-
Prevalence of Inflammatory Bowel Disease Unclassified, as Estimated Using the Revised Porto Criteria, among Korean Pediatric Patients with Inflammatory Bowel Disease
Pediatric Gastroenterology, Hepatology & Nutrition
2024 .07
-
Efficacy evalution of candidate A in DSS-induced inflammatory bowel disease mouse model
한국실험동물학회 학술발표대회 논문집
2022 .07
-
Nutritional aspect of pediatric inflammatory bowel disease: its clinical importance
Clinical and Experimental Pediatrics
2015 .01
-
Trends of inflammatory bowel disease at a tertiary care center in northern India
Intestinal research
2021 .01
-
The Efficiency of Intravenous Iron Therapy in Korean Inflammatory Bowel Disease Patients
Gut and Liver
2016 .01
-
염증성 장질환의 약물요법
대한의사협회지
2015 .01
-
Anxiety and Depression in Patients with Inflammatory Bowel Diseases: The First Step toward Proper Management
Gut and Liver
2020 .01
-
Trends in Healthcare Costs for Inflammatory Bowel Disease in South Korea
Gut and Liver
2020 .01
-
Do We Have an Opportunity to Avoid Opportunistic Infections in Asian Patients with Inflammatory Bowel Disease?
Gut and Liver
2022 .09
-
CM1, a novel chrysin derivative, attenuates inflammatory responses in DSS-induced colitis mice model: Therapeutic potential against inflammatory bowel disease
한국실험동물학회 학술발표대회 논문집
2022 .01
-
Mitochondrial dysfunction of epithelial cell drives submucosal thickening through inflammatory fibroblasts in ulcerative colitis
한국실험동물학회 학술발표대회 논문집
2025 .02
이 논문의 저자 정보
최근 본 자료
댓글(0)
0