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논문 기본 정보

자료유형
학술저널
저자정보
공은정 (Asan Medical Center University of Ulsan College of Medicine) 정기욱 (Department of Gastroenterology University of Ulsan College of Medicine Seoul Korea) Yang Won Min (Department of Medicine Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Kore) Kyoung Sup Hong (Seoul National University College of Medicine Seoul Korea) Hye-Kyung Jung (Department of Internal Medicine Ewha Womans University College of Medicine Seoul Korea) Hee Jung Son (Department of Gastroenterology Samsung Medical Center Seoul Korea) Do Yeon Kim (Department of Gastroenterology University of Ulsan College of Medicine Asan Medical Center Korea) Jungbok Lee (Department of Clinical Epidemiology and Biostatistics Asan Medical Center Seoul Korea) Oh Young Lee (Department of Internal Medicine Hanyang University College of Medicine Seoul Korea)
저널정보
대한소화관운동학회(현 대한소화기능성질환.운동학회) Journal of Neurogastroenterology and Motility (JNM) Journal of Neurogastroenterology and Motility (JNM) Vol.25 No.1
발행연도
2019.1
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91 - 99 (9page)

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Background/Aims The Gastroesophageal Reflux Disease Questionnaire (GerdQ) has been developed and validated as a tool for the diagnosis of gastroesophageal reflux disease (GERD) in patients with gastrointestinal symptoms. However, the GerdQ and the cutoff value for determining GERD has not been validated in Korea. Methods Patients with symptoms suggestive of GERD were consecutively recruited. The Korean version of GerdQ was developed through a forward-backward translation process according to the cross-cultural adaptation method. Endoscopically documented esophagitis, abnormal results on 24-hour ambulatory pH recording with symptom association monitoring, or response to proton pump inhibitor treatment were used as diagnostic references for GERD. The reproducibility and test characteristics of the Korean version of GerdQ were assessed. Results A total of 149 patients with a median age of 55 years were analyzed. The intra-class correlation coefficient of 2 subsequently measured GerdQ scores was 0.651 (95% CI, 0.518–0.748). The cutoff value of 8 was found to have the highest sensitivity (64.9%; 95% CI, 56.2–73.7) and specificity (71.4%; 95% CI, 56.5–86.4) for the diagnosis of GERD. The questionnaire had a high positive predictive value (88.1%; 95% CI, 81.2–95.0), but a low negative predictive value (38.5%; 95% CI, 26.2–50.3) for GERD. Any symptom improvement on proton pump inhibitor treatment showed a sensitivity of 93.0% (95% CI, 88.3–97.7) and a specificity of 48.6% (95% CI, 32.0–65.1) for GERD. Conclusion The Korean version of GerdQ is a useful complementary tool in the diagnosis of GERD.
#Gastroesophageal reflux #Surveys and questionnaires #Symptom assessment

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참고문헌 (33)

참고문헌 신청
Vakil N / 2006 / The montreal definition and classification of gastroesophageal reflux disease : a global evidence-based consensus / Am J Gastroenterol 101:1900~1920 google schola El-Serag HB / 2014 / Update on the epidemiology of gastro-oesophageal reflux disease : a systematic review / Gut 63:871~880 google schola Kim KM / 2012 / Prevalence of gastroesophageal reflux disease in Korea and associated health-care utilization : a national population-based study / J Gastroenterol Hepatol 27:741~745 google schola Min BH / 2014 / Prevalence of uninvestigated dyspepsia and gastroesophageal reflux disease in Korea : a population-based study using the Rome III criteria / Dig Dis Sci 59:2721~2729 google schola Katz PO / 2013 / Guidelines for the diagnosis and management of gastroesophageal reflux disease / Am J Gastroenterol 108:308~328 google schola

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