Repair of Iliac Crest Defects with a Hydroxyapatite/Collagen Composite

Murata Koichi; Fujibayashi Shunsuke; Otsuki Bungo; Shimizu Takayoshi; Matsuda Shuichi

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자료유형: 학술저널

저자정보: Murata Koichi (Kyoto University Graduate School of Medicine) Fujibayashi Shunsuke (Kyoto University Graduate School of Medicine) Otsuki Bungo (Kyoto University Graduate School of Medicine) Shimizu Takayoshi (Kyoto University Graduate School of Medicine) Matsuda Shuichi (Kyoto University Graduate School of Medicine)

저널정보: 대한척추외과학회 Asian Spine Journal Asian Spine Journal Vol.14 No.6

발행연도: 2020.1

수록면: 808 - 813 (6page)

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Study Design: Retrospective study.Purpose: This study aimed to assess the effect of refilling with hydroxyapatite/collagen (HAp/Col) composite on an iliac crest defect after spinal fusion.Overview of Literature: The use of iliac crest bone graft has been the gold standard in spinal fusion for a long time because of its biological and non-immunologic properties. Few reports have addressed how bone defects recover after iliac crest bone harvest following spinal fusion.Methods: Cancellous bone was collected from the anterior iliac crest during lateral interbody fusion (LIF), and the bone void of the ilium was refilled with a porous HAp/Col composite. We assessed bone recovery using computed tomography (CT). From the 74 patients who underwent LIF between January 2015 and December 2016, we included 49 patients whose iliac crest could be evaluated using CT at 3 months and 1 year after the surgery.Results: Bone defects decreased in a time-dependent manner after the surgery. Cortical closure was observed in 28.5% of the cases 3 months after the surgery; at 1 year postoperatively, 95.9% of the patients had cortical closure. Complete repair of the cancellous bone was achieved in 57.1% of the patients at 3 months after the surgery and in 95.9% at 1 year after the surgery. There were no significant hematomas, infections, iliac crest fractures, or soft tissue herniation.Conclusions: Radiographic recovery of cortical and cancellous bone defects was achieved with high probability via refilling with HAp/Col composite over the 1-year period.

#Ilium #Bone regeneration #Hydroxyapatites #Collagen type 1

참고문헌 (23)

참고문헌 신청

Fujibayashi S / 2015 / Effect of indirect neural decompression through oblique lateral interbody fusion for degenerative lumbar disease / Spine 40:E175~E182

Duarte RM / 2017 / Biomaterials and bioactive agents in spinal fusion / Tissue Eng Part B Rev 23:540~551

Morris MT / 2018 / Bone graft materials for posterolateral fusion made simple : a systematic review / Eur Spine J 27:1856~1867

Myeroff C / 2011 / Autogenous bone graft : donor sites and techniques / J Bone Joint Surg Am 93:2227~2236

Burton DC / 2013 / Backfill-ing of iliac crest defects with hydroxyapatite-calcium triphosphate biphasic compound : a prospective, randomized computed tomography and patient-based analysis / Spine J 13:54~61

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