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논문 기본 정보

자료유형
학술저널
저자정보
추일한 (조선대학교 의과대학 신경정신과학교실)
저널정보
대한노인정신의학회 노인정신의학 노인정신의학 제25권 제1호
발행연도
2021.1
수록면
8 - 13 (6page)

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초록· 키워드

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Objective: Mild cognitive impairment (MCI) is transitional state between cognitively normal and dementia. It is not easy to detect MCI patient early in the community. This study aimed to detect MCI early performing learning memory tests of neuropsychological test domains in the community sample. Methods: Overall 7,307 individuals were already registered with Korean version of Mini-Mental Status Examination for Dementia Screening (MMSE-DS) evaluation. It was conducted across all 5 districts of Gwangju, Republic of Korea from April 1, 2020 to September 30, 2020. As first step, we screened them applying inclusion criteria of age, sex, education adjusted norm based MMSE Z score between -1.5 and 0, and MMSE delayed recall score less than 2. And second assessments of neuropsychological tests and clinical diagnosis with visit were performed. We examined whether verbal and constructional learning memory tests can improve the detection of MCI by receiver operating curve (ROC) analysis. Results: Clinical diagnosis finally defined 100 amnestic MCI, 8 non-amnestic MCI and 6 cognitively normal (CN). Visual immediate and delayed recall test had the highest ROC overall accuracy of 79.2% (95% confidence interval 67.8-90.6%) differentiating MCI from CN. Conclusion: Our study suggests that visual immediate recall test might be time saving and cost-effective in addition to accuracy to early detect MCI in the community.

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