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논문 기본 정보

자료유형
학술저널
저자정보
Jin Uk Choi (Asan Medical Center University of Ulsan College of Medicine Seoul Korea) Shin Hwang (Asan Medical Center University of Ulsan College of Medicine Seoul Korea) I-Ji Chung (University of Ulsan) Sang-Hyun Kang (Asan Medical Center University of Ulsan College of Medicine Seoul Korea) Chul-Soo Ahn (Asan Medical Center University of Ulsan College of Medicine Seoul Korea) Deok-Bog Moon (Asan Medical Center University of Ulsan College of Medicine Seoul Korea) Tae Yong Ha (Asan Medical Center University of Ulsan College of Medicine Seoul) Ki-Hun Kim (Asan Medical Center University of Ulsan College of Medicine Seoul Korea) Gi Won Song (Asan Medical Center University of Ulsan College of Medicine) Dong-Hwan Jung (Asan Medical Center University of Ulsan College of Medicine Seoul Korea) Gil-Chun Park (Asan Medical Center University of Ulsan College of Medicine Seoul Korea) Young-In Yoon (Asan Medical Center University of Ulsan College of Medicine Seoul Korea) Hui-Dong Cho (Asan Medical Center University of Ulsan College of Medicine Seoul Korea) Sung Gyu Lee (Asan Medical Center University of Ulsan College of Medicine)
저널정보
대한이식학회 Clinical Transplantation and Research Korean Journal of Transplantation Vol.34 No.1
발행연도
2020.1
수록면
55 - 61 (7page)

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초록· 키워드

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Background: Living donor liver transplantation (LDLT) causes bleeding in recipients during the careful preservation of most perihilar structures during this surgery. This case-control study aimed to analyze the effect of prolonged hepatic inflow occlusion (PHIO) when applied during recipient hepatectomy in LDLT. Methods: The study group comprised patients who underwent PHIO with Model for End-Stage Liver Disease (MELD) scores ranging from 26 to 35 (n=20). The following two control groups were selected according to their MELD scores: the low-MELD score group (MELD scores of 15–20, n=40) and the high-MELD score group (MELD scores of 26–35, n=40). Total dissection time for hepatic mobilization and dissection and blood loss during these procedures were compared between the two groups. Results: In the PHIO study group, mean total dissection time and mean PHIO duration were 226.3±59.4 and 68.2±19.1 minutes, respectively. Twelve patients underwent PHIO twice, and the other eight patients underwent PHIO once. The low-MELD score control group and the PHIO study group showed similar dissection duration (216.0±43.9 vs. 226.3±59.4 minutes, P=0.82) and similar blood loss volume during dissection (2,112.5±1,614.9 vs. 2,350.0±951.9 mL, P=0.17). The high-MELD score control group and the PHIO study group showed similar dissection duration (241.0±41.9 vs. 226.3±59.4 minutes, P=0.71), but the PHIO group showed a significantly lower blood loss during dissection than the high-MELD score group (2,350.0±951.9 vs. 2,815.0±1,813.9 mL, P=0.002). During and after PHIO, no adverse complication was observed, except for transient splanchnic congestion. Conclusions: Our findings suggest that PHIO is a simple effective method to reduce intraoperative bleeding during hepatic mobilization and dissection during LDLT operation requiring difficult dissection.

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