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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 128 - 134 (7page)
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Background: Patients who undergo reoperation after living-donor liver transplantation (LDLT) have poor outcomes. However, the specific outcomes of patients undergoing reoperation due to gastrointestinal (GI) tract-related complications following adult LDLT are relatively unknown. In the present study, we investigated the relationship between the causes and outcomes of reoperation after LDLT and classified the risk groups. Methods: We performed a retrospective analysis of 506 patients who underwent LDLT at Samsung Medical Center in Seoul between 2010 and 2016. Results: Among 506 adult LDLT recipients, 98 (19.4%) underwent reoperation. The causes for reoperation included bleeding (n=39, 39.8%), vascular complications (n=26, 26.5%), wound complications (n=12, 12.2%), bile leakage (n=7, 7.1%), GI tract complications (n=6, 6.1%), and others (n=8, 8.1%). Based on a multivariate analysis, we identified prolonged operation time, hospitalization days, and a history of previous hepatocellular carcinoma-related operation as independent risk factors for reoperation. Patient survival after 3 months, 1 year, 3 years, and 5 years was 96.3%, 90.6%, 82.5%, and 79.4% in the non-reoperation group and 95.9%, 82.7%, 72.8% and 69.3% in the reoperation group, respectively. Patient survival in the reoperation group was significantly lower than that in the non-reoperation group (P=0.018). In the reoperation group, the survival rates of patients with GI tract-related complications—including bile leakage and GI tract complications—were significantly worse than those of patients with non-GI tract-related complications such as bleeding, vascular complications, and wound complications (P＜0.001). Conclusions: Our results showed that patient outcomes are poor after early reoperation after LDLT and that patients with GI tract-related complications have a higher risk of mortality.
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참고문헌 (22)
참고문헌 신청
Ogawa K / 2016 / Living vs. deceased-donor liver transplantation for patients with hepatocellular carcinoma / Transl Gastroenterol Hepatol 1:35
Li C / 2011 / Outcomes of patients with benign liver diseases undergoing living donor versus deceased donor liver transplantation / PLoS One 6:e27366
Chen CL / 2013 / Why does living donor liver transplantation flourish in Asia? / Nat Rev Gastroenterol Hepatol 10:746~751
Bozkurt B / 2017 / Living donor liver transplantation / Chirurgia (Bucur) 112:217~228
Freise CE / 2008 / Recipient morbidity after living and deceased donor liver transplantation: findings from the A2ALL Retrospective Cohort Study / Am J Transplant 8:2569~2579
Li C / 2011 / Outcomes of patients with benign liver diseases undergoing living donor versus deceased donor liver transplantation / PLoS One 6:e27366
Chen CL / 2013 / Why does living donor liver transplantation flourish in Asia? / Nat Rev Gastroenterol Hepatol 10:746~751
Bozkurt B / 2017 / Living donor liver transplantation / Chirurgia (Bucur) 112:217~228
Freise CE / 2008 / Recipient morbidity after living and deceased donor liver transplantation: findings from the A2ALL Retrospective Cohort Study / Am J Transplant 8:2569~2579
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