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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 93 - 102 (10page)
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Purpose: The purpose of this study was to evaluate the predictive performance of ultrasonography (US)-based radiomics for axillary lymph node metastasis and to compare it with that of a clinicopathologic model. Methods: A total of 496 patients (mean age, 52.5±10.9 years) who underwent breast cancer surgery between January 2014 and December 2014 were included in this study. Among them, 306 patients who underwent surgery between January 2014 and August 2014 were enrolled as a training cohort, and 190 patients who underwent surgery between September 2014 and December 2014 were enrolled as a validation cohort. To predict axillary lymph node metastasis in breast cancer, we developed a preoperative clinicopathologic model using multivariable logistic regression and constructed a radiomics model using 23 radiomic features selected via least absolute shrinkage and selection operator regression. Results: In the training cohort, the areas under the curve (AUC) were 0.760, 0.812, and 0.858 for the clinicopathologic, radiomics, and combined models, respectively. In the validation cohort, the AUCs were 0.708, 0.831, and 0.810, respectively. The combined model showed significantly better diagnostic performance than the clinicopathologic model. Conclusion: A radiomics model based on the US features of primary breast cancers showed additional value when combined with a clinicopathologic model to predict axillary lymph node metastasis.
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참고문헌 (26)
참고문헌 신청
Jatoi I / 1999 / Significance of axillary lymph node metastasis in primary breast cancer / J Clin Oncol 17:2334~2340
Lyman GH / 2005 / American Society of Clinical Oncology guideline recommendations for sentinel lymph node biopsy in earlystage breast cancer / J Clin Oncol 23:7703~7720
Del Bianco P / 2008 / Morbidity comparison of sentinel lymph node biopsy versus conventional axillary lymph node dissection for breast cancer patients: results of the sentinella-GIVOM Italian randomised clinical trial / Eur J Surg Oncol 34:508~513
Kataria K / 2016 / What is a false negative sentinel node biopsy: definition, reasons and ways to minimize it? / Indian J Surg 78:396~401
Lee MC / 2012 / Axillary staging prior to neoadjuvant chemotherapy: the roles of sentinel lymph node biopsy and axillary ultrasonography / Cancer Control 19:277~285
Lyman GH / 2005 / American Society of Clinical Oncology guideline recommendations for sentinel lymph node biopsy in earlystage breast cancer / J Clin Oncol 23:7703~7720
Del Bianco P / 2008 / Morbidity comparison of sentinel lymph node biopsy versus conventional axillary lymph node dissection for breast cancer patients: results of the sentinella-GIVOM Italian randomised clinical trial / Eur J Surg Oncol 34:508~513
Kataria K / 2016 / What is a false negative sentinel node biopsy: definition, reasons and ways to minimize it? / Indian J Surg 78:396~401
Lee MC / 2012 / Axillary staging prior to neoadjuvant chemotherapy: the roles of sentinel lymph node biopsy and axillary ultrasonography / Cancer Control 19:277~285
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