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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 376 - 383 (8page)
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Purpose: Excision of metastatic lesions is an important treatment strategy in patients with malignant melanoma, both at the initial diagnosis and upon recurrence. Since nonpalpable lesions cannot be easily visualized in the surgical field, we evaluated the effectiveness of ultrasound (US)-guided tattooing using a charcoal suspension for the localization of nonpalpable metastatic lesions of malignant melanoma. Methods: Between November 2009 and June 2019, we retrospectively reviewed 65 nonpalpable lesions in 29 patients with malignant melanoma who underwent preoperative US-guided tattooing using a charcoal suspension for histologically confirmed or suspected metastases. The characteristics of the tattooed lesions were analyzed. The effectiveness of the procedure was evaluated based on the detection rate in the surgical field and the presence or absence of residua on postoperative follow-up US. Procedure-related complications were also analyzed. Results: Of 65 lesions, 33 (50.8%) were histologically confirmed as metastases before the tattooing procedure, while the other 32 were suspected of being metastases based on imaging studies. The mean lesion size was 9.8 mm (range, 1.3 to 24.4 mm). The final pathology revealed metastases in 59 lesions (90.8%), including lymph node (n=51), muscle (n=5), and in-transit (n=3) metastases. Sixty-one lesions (93.8%) were successfully detected intraoperatively and removed without residua on follow-up US. Four residual lesions were removed after repeated localization (n=2) or by intraoperative US (n=2). No relevant complications were noted. Conclusion: Preoperative US-guided tattooing localization can safely and effectively delineate nonpalpable metastatic melanoma lesions to aid in successful surgical excision.
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참고문헌 (38)
참고문헌 신청
Garbe C / 2016 / Diagnosis and treatment of melanoma. European consensusbased interdisciplinary guideline: update 2016 / Eur J Cancer 63:201~217
Pflugfelder A / 2013 / Malignant melanoma S3-guideline "diagnosis, therapy and follow-up of melanoma" / J Dtsch Dermatol Ges 11(Suppl 6):1~116
Ghaferi AA / 2009 / Prognostic significance of a positive nonsentinel lymph node in cutaneous melanoma / Ann Surg Oncol 16:2978~2984
Leiter U / 2016 / Complete lymph node dissection versus no dissection in patients with sentinel lymph node biopsy positive melanoma (DeCOG-SLT): a multicentre, randomised, phase 3 trial / Lancet Oncol 17:757~767
Grotz TE / 2011 / In-transit melanoma: an individualized approach / Oncology (Williston Park) 25:1340~1348
Pflugfelder A / 2013 / Malignant melanoma S3-guideline "diagnosis, therapy and follow-up of melanoma" / J Dtsch Dermatol Ges 11(Suppl 6):1~116
Ghaferi AA / 2009 / Prognostic significance of a positive nonsentinel lymph node in cutaneous melanoma / Ann Surg Oncol 16:2978~2984
Leiter U / 2016 / Complete lymph node dissection versus no dissection in patients with sentinel lymph node biopsy positive melanoma (DeCOG-SLT): a multicentre, randomised, phase 3 trial / Lancet Oncol 17:757~767
Grotz TE / 2011 / In-transit melanoma: an individualized approach / Oncology (Williston Park) 25:1340~1348
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