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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 162 - 170 (9page)
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Purpose: Isometric handgrip exercise (IHE) is an easy and accessible form of exercise that has beneficial effects on blood pressure (BP). However, it remains unclear whether IHE is similar benefits on arterial stiffness and endothelial function compared with aerobic exercise (AE) in elderly hypertensive patients. The aim of this study was to compare the effects of IHE versus AE on arterial stiffness and endothelial function in elderly hypertensive patients. Methods: We conducted a randomized controlled trial with a three-arm design. Fifty-four elderly hypertensive patients (15 men; mean age, 69±6 years; systolic blood pressure, 131.2±14.7; diastolic blood pressure, 80.2±7.9 mm Hg) were randomized to IHE training (n=18), AE training (n=21), or non-exercise control group (n=21) for 12 weeks. Bilateral IHE training was performed four times of 2 minutes at 30% of maximal voluntary contraction with three times per week. AE training was performed brisk walking for 30 minutes at moderate intensity with three times per week. Carotid-femoral pulse wave velocity (PWV), augmentation index heart rate corrected (AIx@75 bpm) and brachial artery flow-mediated vasodilation (FMD) as indices of arterial stiffness and endothelial function were measured at baseline and after the intervention. Results: Following 12-week intervention, resting BP was significantly decreased in both IHE (p=0.001) and AE groups (p=0.002). AIx@75 bpm and FMD were unchanged in the all groups. However, PWV was significantly decreased in both IHE and AE groups (IHE, 10.9±2.3 to 9.9±2.1 m/s [p＜0.001]; AE, 10.5±2.0 to 9.4±1.6 m/s [p=0.001]), without any change in the control group. Conclusion: These findings suggest that both IHE and AE trainings were comparable effect in improving arterial stiffness in elderly hypertensive patients.
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참고문헌 (29)
참고문헌 신청
Chung K / 2018 / 2017 National survey of older Koreans: findings and implications
Mancia G / 2013 / 2013 ESH/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) / J Hypertens 31:1281~1357
Pescatello LS / 2004 / American College of Sports Medicine position stand: exercise and hypertension / Med Sci Sports Exerc 36:533~553
Millar PJ / 2014 / Evidence for the role of isometric exercise training in reducing blood pressure: potential mechanisms and future directions / Sports Med 44:345~356
Carlson DJ / 2014 / Isometric exercise training for blood pressure management: a systematic review and meta-analysis / Mayo Clin Proc 89:327~334
Mancia G / 2013 / 2013 ESH/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) / J Hypertens 31:1281~1357
Pescatello LS / 2004 / American College of Sports Medicine position stand: exercise and hypertension / Med Sci Sports Exerc 36:533~553
Millar PJ / 2014 / Evidence for the role of isometric exercise training in reducing blood pressure: potential mechanisms and future directions / Sports Med 44:345~356
Carlson DJ / 2014 / Isometric exercise training for blood pressure management: a systematic review and meta-analysis / Mayo Clin Proc 89:327~334
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