지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한비만학회 Journal of Obesity & Metabolic Syndrome Journal of Obesity & Metabolic Syndrome Vol.28 No.2
- 발행연도
- 2019.1
- 수록면
- 112 - 117 (6page)
이용수
초록· 키워드
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Background: Previous epidemiologic studies showed that obesity increased the risk of diabetic peripheral neuropathy (DPN). However, there is very limited data about the impact of body fat measured by body composition analysis in DPN. Methods: Subjects with type 2 diabetes mellitus (T2DM) between 20 to 55 years old were enrolled. DPN was diagnosed using the Michigan Neuropathy Screening Instrument. Body composition was assessed by bio-impedance analysis, and the association between body composition and DPN was investigated. Results: Among 65 subjects, 44.6% were diagnosed with DPN. Subjects with DPN had higher body mass index and waist circumference than subjects without DPN. Body composition data showed that fat mass, fat percent, and visceral fat area were higher in subjects with DPN than in subjects without DPN. Furthermore, the presence of DPN was associated with waist circumference (odds ratio [OR], 1.151; 95% confidence interval [CI], 1.055–1.256; P=0.002), visceral fat area (OR, 1.026; 95% CI, 1.005–1.048; P=0.015), and insulin resistance (OR, 1.673; 95% CI, 1.091–2.565; P=0.018) after adjusting age, sex, diabetes duration, and smoking status. Conclusion: Abdominal obesity was associated with DPN. Insulin resistance might mediate obesity and DPN in middle aged subjects with T2DM.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Pop-Busui R / 2017 / Diabetic neuropathy: a position statement by the American Diabetes Association / Diabetes Care 40:136~154
Tesfaye S / 2005 / Vascular risk factors and diabetic neuropathy / N Engl J Med 352:341~350
Andersen ST / 2018 / Risk factors for the presence and progression of cardiovascular autonomic neuropathy in type 2 diabetes:ADDITION-Denmark / Diabetes Care 41:2586~2594
Look AHEAD Research Group / 2017 / Effects of a long-term lifestyle modification programme on peripheral neuropathy in overweight or obese adults with type 2 diabetes: the Look AHEAD study / Diabetologia 60:980~988
Alberti KG / 2006 / Metabolic syndrome: a new world-wide definition. A Consensus Statement from the International Diabetes Federation / Diabet Med 23:469~480
Tesfaye S / 2005 / Vascular risk factors and diabetic neuropathy / N Engl J Med 352:341~350
Andersen ST / 2018 / Risk factors for the presence and progression of cardiovascular autonomic neuropathy in type 2 diabetes:ADDITION-Denmark / Diabetes Care 41:2586~2594
Look AHEAD Research Group / 2017 / Effects of a long-term lifestyle modification programme on peripheral neuropathy in overweight or obese adults with type 2 diabetes: the Look AHEAD study / Diabetologia 60:980~988
Alberti KG / 2006 / Metabolic syndrome: a new world-wide definition. A Consensus Statement from the International Diabetes Federation / Diabet Med 23:469~480
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