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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 187 - 193 (7page)
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Purpose: No guidelines exist detailing when to implement a temporary ileostomy closure in the setting of adjuvant chemotherapy following sphincter-saving surgery for rectal cancer. The aim of this study was to evaluate the clinical and oncological outcomes of ileostomy closure during adjuvant chemotherapy in patients with curative resection of rectal cancer. Methods: This retrospective study investigated 220 patients with rectal cancer undergoing sphincter-saving surgery with protective loop ileostomy from January 2007 to August 2016. Patients were divided into 2 groups: group 1 (n = 161) who underwent stoma closure during adjuvant chemotherapy and group 2 (n = 59) who underwent stoma closure after adjuvant chemotherapy. Results: No significant differences were observed in operative time, blood loss, postoperative hospital stay, or postoperative complications in ileostomy closure between the 2 groups. No difference in overall survival (P = 0.959) or disease-free survival (P = 0.114) was observed between the 2 groups. Conclusion: Ileostomy closure during adjuvant chemotherapy was clinically safe, and interruption of chemotherapy due to ileostomy closure did not change oncologic outcomes.
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등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Matthiessen P / 2007 / Defunctioning stoma reduces symptomatic anastomotic leakage after low anterior resection of the rectum for cancer : a randomized multicenter trial / Ann Surg 246:207~214
Hüser N / 2008 / Systematic review and meta-analysis of the role of defunctioning stoma in low rectal cancer surgery / Ann Surg 248:52~60
Tan WS / 2009 / Meta-analysis of defunctioning stomas in low anterior resection for rectal cancer / Br J Surg 96:462~472
Giannakopoulos GF / 2009 / Morbidity and complications of protective loop ileostomy / Colorectal Dis 11:609~612
Akesson O / 2012 / Morbidity related to defunctioning loop ileostomy in low anterior resection / Int J Colorectal Dis 27:1619~1623
Hüser N / 2008 / Systematic review and meta-analysis of the role of defunctioning stoma in low rectal cancer surgery / Ann Surg 248:52~60
Tan WS / 2009 / Meta-analysis of defunctioning stomas in low anterior resection for rectal cancer / Br J Surg 96:462~472
Giannakopoulos GF / 2009 / Morbidity and complications of protective loop ileostomy / Colorectal Dis 11:609~612
Akesson O / 2012 / Morbidity related to defunctioning loop ileostomy in low anterior resection / Int J Colorectal Dis 27:1619~1623
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