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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 317 - 324 (8page)
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초록· 키워드
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Introduction It has been reported that various plant species may enhance the elimination of fatigue-related metabolites. However, relatively few studies have directly addressed the potential anti-fatigue effects. Objective The objective of this study was to investigate the anti-fatigue potential of a hot water extract of Sasa quelpaertensis Nakai leaf (SQH) in male ICR mice. Methods The animals were divided into three groups. The normal control (NC) group was administered saline without exercise every day for 7 days. The exercise control (EC) and exercise with SQH (ES) groups were administered saline and SQH (50 mg/kg of body weight), respectively, every day for 7 days and underwent swimming exercise. RNA sequencing technology was used to analyze the transcriptome profiles of muscle. Results Swimming times were prolonged in the ES group compared with the EC group. The ES group had higher blood glucose and lower blood lactate levels, and higher muscular glycogen and lower muscular lactate levels, compared with the EC group. The groups did not differ in histopathological parameters of the muscle and liver, but muscle cell sizes were smaller in the EC group than in the ES and NC groups. RNA sequencing analysis revealed that SQH administration regulated genes associated with energy-generating metabolic pathways in skeletal muscle. Conclusion These results suggest that SQH exerts anti-fatigue properties by balancing various biological systems and helping maintain the basic harmonious pattern of the body.
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등록된 정보가 없습니다.
참고문헌 (32)
참고문헌 신청
Belluardo N / 2001 / Neuromuscular junction disassembly and muscle fatigue in mice lacking neurotrophin-4 / Mol Cell Neurosci 18:56~67
정원석 / 2012 / Anti-fatigue Effect of Fermented Deer Velvet Antler Extract in Sprague-Dawley Rats / 한방재활의학과학회지 22(1):11~22
DeVol DL / 1990 / Activation of insulin-like growth factor gene expression during work-induced skeletal muscle growth / Am J Physiol 259:E89~E95
Dohm GL / 1983 / Influence of fasting on glycogen depletion in rats during exercise / J App Physiol 55:830~833
Gentleman RC / 2004 / Bioconductor: open software development for computational biology and bioinformatics / Genome Biol 45:R80
정원석 / 2012 / Anti-fatigue Effect of Fermented Deer Velvet Antler Extract in Sprague-Dawley Rats / 한방재활의학과학회지 22(1):11~22
DeVol DL / 1990 / Activation of insulin-like growth factor gene expression during work-induced skeletal muscle growth / Am J Physiol 259:E89~E95
Dohm GL / 1983 / Influence of fasting on glycogen depletion in rats during exercise / J App Physiol 55:830~833
Gentleman RC / 2004 / Bioconductor: open software development for computational biology and bioinformatics / Genome Biol 45:R80
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