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논문 기본 정보

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학술저널
저자정보
Seon Jeong-Yeon (Department of Preventive Medicine School of Medicine Kyung Hee University Seoul Korea.) Jeon Woo-Hwi (Department of Preventive Medicine School of Medicine Kyung Hee University Seoul Korea.) Bae Sang-Cheol (Department of Rheumatology Hanyang University Hospital for Rheumatic Diseases Seoul Korea.) Eun Baik-Lin (Department of Pediatrics Korea University Guro Hospital Korea University College of Medicine Seoul) Choung Ji-Tae (Department of Pediatrics Korea University Seoul Korea.) Oh In-Hwan (Department of Preventive Medicine School of Medicine Kyung Hee University Seoul Korea.)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.36 No.20
발행연도
2021.1
수록면
1 - 13 (13page)

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Background: Based on the reports of low prevalence and severity of pediatric severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, the Korean government has released new SARS-CoV-2 infection response and treatment guidelines for children under the age of 12 years. The government has further directed school reopening under strict preventive measures. However, there is still considerable concern on the impact of school reopening on community transmission of Coronavirus disease 2019 (COVID-19). In the present study, we aimed to evaluate the appropriateness of these directives and the severity of SARS-CoV-2 infections in children as compared to adults using sufficient national sample data. Methods: In the present study, we evaluated the severity of SARS-CoV-2 infection in pediatric patients as compared to adults by analyzing the length of hospital stays (LOS), medical expenses, and hospital and intensive care unit (ICU) admission rates. A multivariate linear regression analysis was carried out to examine the effects of COVID-19 patients that the characteristics on the LOS and medical expenses, and multivariate logistic regression analysis were performed to identify COVID-19 characteristics that affect hospital and ICU admission rates and to prove the low SARS-CoV-2 infection severity in pediatric patients. Results: The hospitalization period for children aged 0–9 was 37% shorter and that of patients aged 10–19 years was 31% shorter than those of older age groups (P < 0.001). The analysis of the medical expenses by age showed that on average, medical expenses for children were approximately 4,900 USD lower for children than for patients over 80 years of age. The linear regression analysis also showed that patients who were 0–9 years old spent 87% and those aged 10–19 118% less on medical expenses than those aged 70 and over, even after the correction of other variables (P < 0.001). The probability of hospitalization was the lowest at 10–19 years old (odds ratio [OR], 0.05; 95% confidence interval [CI], 0.03–0.09), and their ICU admission rate was also the lowest at 0.14 (OR, 0.14; 95% CI, 0.08–0.24). On the other hand, the likelihood of hospitalization and ICU admission was the highest in children aged 0–9 years, and among patients under the age of 50 years in general. Conclusion: This study demonstrated the low severity of SARS-CoV-2 infection in younger patients (0–19 years) by analyzing the LOS, medical expenses, hospital, and intensive care unit admission rates as outcome variables. As the possibility to develop severe infection of coronavirus at the age of 10–19 was the lowest, a mitigation policy is also required for middle and high school students. In addition, children with underlying diseases need to be protected from high-risk infection environments.
#COVID-19 Pandemic #Pediatric Patient #Severity of Illness #Preventive Measures

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참고문헌 (25)

참고문헌 신청
Korea Centers for Disease Control and Prevention / The updates on COVID-19 in Korea as of 17 February google schola Dong Y / 2020 / Epidemiology of COVID-19 among children in China / Pediatrics 145(6):e20200702 google schola Wang D / 2020 / Clinical analysis of 31 cases of 2019 novel coronavirus infection in children from six provinces(autonomous region)of northern China / Zhonghua Er Ke Za Zhi 58(4):269~274 google schola COVID-19 Response Team / 2020 / Coronavirus disease 2019 in children—United States, February 12–April 2, 2020 / MMWR Morb Mortal Wkly Rep 69(14):422~426 google schola Han MS / 2021 / Clinical characteristics and viral RNA detection in children with coronavirus disease 2019 in the Republic of Korea / JAMA Pediatr 175(1):73~80 google schola

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