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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 1 - 11 (11page)
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Background: We aimed to validate Baveno VI and expanded Baveno VI criteria using two dimensional shear-wave elastography (2D-SWE) in compensated advanced chronic liver disease (cACLD) patients with alcohol as the main etiology. Methods: Clinical data from 305 patients with cACLD who underwent a liver stiffness measurement (LSM) with 2D-SWE and endoscopy were consecutively collected. Results: Among 305 patients, high-risk varix (HRV) was identified in 21.3% (n = 65). The main etiology was alcoholic liver disease (51.8%), followed by hepatitis B virus (29.8%) and hepatitis C virus (9.1%). Baveno VI criteria spared endoscopy in 118 of the 305 (38.7%) patients, and 7 (5.9%) were missed with HRV. Expanded Baveno VI criteria spared more endoscopies (60.0%), but missed more HRV (9.8%) compared with Baveno VI criteria. The other classification described as the modified Baveno VI criteria were LSM < 25 kPa and PLT ≥ 150 × 103 /mm3 . In total, 131 of the 305 (43.0%) patients were within the modified Baveno VI criteria, of whom seven (5.3%) had missed HRV. After adding spleen diameter < 12 cm to the modified Baveno VI criteria, the number of spared endoscopies increased by 106/305 (34.8%), with three (2.8%) presenting with HRV, indicating a risk of missing HRV. Conclusion: Baveno VI and expanded Baveno VI criteria with 2D-SWE were insufficient with an HRV miss rate of over 5%. The modified Baveno VI criteria with spleen diameters < 12 cm with 2D-SWE spared more endoscopies with a minimal risk of missing HRV in cACLD patients with alcohol as the main etiology.
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참고문헌 (29)
참고문헌 신청
de Franchis R / 2010 / Revising consensus in portal hypertension: report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension / J Hepatol 53(4):762~768
Lin DY / 1993 / Ultrasonographic changes of early liver cirrhosis in chronic hepatitis B : a longitudinal study / J Clin Ultrasound 21(5):303~308
de Franchis R / 2015 / Expanding consensus in portal hypertension: report of the Baveno VI Consensus Workshop: stratifying risk and individualizing care for portal hypertension / J Hepatol 63(3):743~752
Augustin S / 2014 / Detection of early portal hypertension with routine data and liver stiffness in patients with asymptomatic liver disease : a prospective study / J Hepatol 60(3):561~569
Giannini E / 2003 / Platelet count/spleen diameter ratio : proposal and validation of a non-invasive parameter to predict the presence of oesophageal varices in patients with liver cirrhosis / Gut 52(8):1200~1205
Lin DY / 1993 / Ultrasonographic changes of early liver cirrhosis in chronic hepatitis B : a longitudinal study / J Clin Ultrasound 21(5):303~308
de Franchis R / 2015 / Expanding consensus in portal hypertension: report of the Baveno VI Consensus Workshop: stratifying risk and individualizing care for portal hypertension / J Hepatol 63(3):743~752
Augustin S / 2014 / Detection of early portal hypertension with routine data and liver stiffness in patients with asymptomatic liver disease : a prospective study / J Hepatol 60(3):561~569
Giannini E / 2003 / Platelet count/spleen diameter ratio : proposal and validation of a non-invasive parameter to predict the presence of oesophageal varices in patients with liver cirrhosis / Gut 52(8):1200~1205
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