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Sensitive Detection of Nucleic Acid Biomarkers Using Transcription Mediated Isothermal Amplification
Sensitive Detection of Nucleic Acid Biomarkers Using Transcription Mediated Isothermal Amplification
논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 480 - 480 (1page)
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Sensitive Detection of Nucleic Acid Biomarkers Using Transcription Mediated Isothermal Amplification
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Nucleic acid biomarkers such as microRNAs (miRNA) involved in various biological processes can be used for early diagnosis and prognosis of various cancers. Quantitative reverse transcription PCR is the gold standard method to detect nucleic acid biomarkers in clinical settings, but it requires expensive equipment and complicated primer designs, thus hindering its use in the field. Herein, we developed a simple, cost-effective strategy for the multiplex detection of nucleic acid biomarkers using light-up RNA aptamers as the key detection component. In principle, the presence of target nucleic acids produces a large amount of light-up RNA aptamers such ... 전체 초록 보기
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