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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 435 - 435 (1page)
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Statins inhibit the 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMG-CoA reductase), which plays a central role in the cholesterol production. They reduce cardiovascular disease and mortality in those who are at high risk of cardiovascular disease. Monacolin J is a statin compound as a lovastatin precursor. It is found in red yeast rice with various strains of the yeast Monascus purpureus. Monacolin J has a hydroxyl substituent at position C’-8 of monacolin L. This study was conducted to synthesize new statin compounds from monacolin J through bacterial CYP102A1 catalysis. Here we found ... 전체 초록 보기
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