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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 395 - 395 (1page)
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초록· 키워드
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Violacein is a naturally occurring purple pigment with antibiotic properties. Violacein is synthesized from tryptophan, so sufficient tryptophan biosynthesis is the key to violacein production. However, tryptophan overproduction in Escherichia coli is challenging due to the complicated biosynthetic pathways and regulatory mechanisms. In this study, we used the adaptive laboratory evolution (ALE) strategy to improve violacein production from galactose. During the ALE, a tryptophan-responsive biosensor was employed to enrich tryptophan-producing cells. After six-rounds of evolution, we transfo ... 전체 초록 보기
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